Results 31 to 40 of about 221,630 (309)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Scattering From Chiral Cylinders of Arbitrary Cross-Sections Above a Ground Plane
The main purpose of this work is to solve the problem of electromagnetic scattering from a chiral cylinder of arbitrary cross-section above an infinite perfect electric conducting (PEC) plane.
Ahsan Altaf +3 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
On two resolvent matrices of the truncated Hausdorff matrix moment problem
We consider the truncated Hausdorff matrix moment problem (THMM) in case of a finite number of even moments to be called non degenerate if two block Hankel matrices constructed via the moments are both positive definite matrices.
A. E. Choque-Rivero +1 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
On truncated and full classical Markov moment problems [PDF]
Octav Olteanu
doaj +1 more source
Non-contact underwater explosion can generate violent movement on hull girders,which may cause longitudinal strength problems. The explosion bending moment can be calculated using a detailed finite element ship model,but this costs considerable working ...
WU Guangming +3 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Estimation of Nonparametric Conditional Moment Models with Possibly Nonsmooth Moments [PDF]
This paper studies nonparametric estimation of conditional moment models in which the residual functions could be nonsmooth with respect to the unknown functions of endogenous variables.
Demian Pouzo, Xiaohong Chen
core +2 more sources
Application of ferroelectric materials for improving output power of energy harvesters
In terms of advances in technology, especially electronic devices for human use, there are needs for miniaturization, low power, and flexibility. However, there are problems that can be caused by these changes in terms of battery life and size.
Tae Yun Kim, Sung Kyun Kim, Sang-Woo Kim
doaj +1 more source

