Results 41 to 50 of about 5,782,493 (298)

Estimation of nonparametric conditional moment models with possibly nonsmooth moments [PDF]

This paper studies nonparametric estimation of conditional moment models in which the residual functions could be nonsmooth with respect to the unknown functions of endogenous variables.
Demian Pouzo, Xiaohong Chen
core   +2 more sources

Using synchronous Boolean networks to model several phenomena of collective behavior.

PLoS ONE, 2014
In this paper, we propose an approach for modeling and analysis of a number of phenomena of collective behavior. By collectives we mean multi-agent systems that transition from one state to another at discrete moments of time. The behavior of a member of
Stepan Kochemazov, Alexander Semenov
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

An algorithm for LES of premixed compressible flows using the Conditional Moment Closure model [PDF]

, 2011
A novel numerical method has been developed to couple a recent high order accurate fully compressible upwind method with the Conditional Moment Closure combustion model. The governing equations, turbulence modelling and numerical methods are presented
Bilger, R. W., R.W. Bilger, Thornber, Ben, Hawkes, E. R., B. Thornber, A.R. Masri, Masri, A. R., E.R. Hawkes   +7 more
core   +1 more source

Piecewise SOS-convex moment optimization and applications via exact semi-definite programs

EURO Journal on Computational Optimization
This paper presents exact Semi-Definite Program (SDP) reformulations for infinite-dimensional moment optimization problems involving a new class of piecewise Sum-of-Squares (SOS)-convex functions and projected spectrahedral support sets.
Q.Y. Huang, V. Jeyakumar, G. Li
doaj   +1 more source

Hausdorff moment problem via fractional moments [PDF]

Applied Mathematics and Computation, 2003
We outline an efficient method for the reconstruction of a probability density function from the knowledge of its infinite sequence of ordinary moments. The approximate density is obtained resorting to maximum entropy technique, under the constraint of some fractional moments. The latter ones are obtained explicitly in terms of the infinite sequence of
Novi Inverardi, Pier Luigi, G. Pontuale, A. Petri, Tagliani, Aldo   +3 more
openaire   +5 more sources

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

The pth Moment Exponential Synchronization of Drive-Response Memristor Neural Networks Subject to Stochastic Perturbations

Complexity, 2023
In this paper, the pth moment exponential synchronization problems of drive-response stochastic memristor neural networks are studied via a state feedback controller.
Xiaobo Wang, Xuefei Wu, Zhe Nie, Zengxian Yan   +3 more
doaj   +1 more source