Results 51 to 60 of about 5,782,493 (298)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Knee adduction moment and medial contact force - facts about their correlation during gait [PDF]

open access: yes, 2013
The external knee adduction moment is considered a surrogate measure for the medial tibiofemoral contact force and is commonly used to quantify the load reducing effect of orthopedic interventions. However, only limited and controversial data exist about
Bergmann, Georg   +7 more
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

The Approximate Solution of Some Plane Boundary Value Problems of the Moment Theory of Elasticity

open access: yesAdvances in Mathematical Physics, 2016
We consider a two-dimensional system of differential equations of the moment theory of elasticity. The general solution of this system is represented by two arbitrary harmonic functions and solution of the Helmholtz equation.
Roman Janjgava
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Applying the Moment Generating Functions to the Study of Probability Distributions [PDF]

open access: yesInformatică economică, 2007
In this paper, we describe a tool to aid in proving theorems about random variables, called the moment generating function, which converts problems about probabilities and expectations into problems from calculus about function values and derivates.
doaj  

The Nevanlinna matrix of the truncated Hausdorff matrix moment problem via orthogonal matrix polynomials on [a,b] for the case of an even number of moments

open access: yesVisnik Harkivsʹkogo Nacionalʹnogo Universitetu im. V.N. Karazina. Cepiâ Matematika, Prikladna Matematika i Mehanika
The scalar moment problem was first introduced by T. J. Stieltjes in his work ``Recherches sur les fractions continues'' Annals of the Faculty of Sciences of Toulouse 8, 1--122, (1895).
Б. Е. Медіна-Ернандес
doaj   +1 more source

On certain non-unique solutions of the Stieltjes moment problem [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2010
We construct explicit solutions of a number of Stieltjes moment problems based on moments of the form ${\rho}_{1}^{(r)}(n)=(2rn)!$ and ${\rho}_{2}^{(r)}(n)=[(rn)!]^{2}$, $r=1,2,\dots$, $n=0,1,2,\dots$, \textit{i.e.} we find functions $W^{(r)}_{1,2}(x)>0$
K. A. Penson   +4 more
doaj   +1 more source

On a Nonlinear Moments Problem

open access: yesJournal of Mathematical Analysis and Applications, 1993
The author investigates the problem to determine a function \(u\in C[a,b]\) if the value of the integral \[ I(g;u):=\int^ b_ ag(u(x))dx \] is known for all \(g\in C(\mathbb{R})\) or only those \(g\) belonging to some countable subset of \(C(\mathbb{R})\). Actually, the existence of a bounded-variation function \(\mu(x;u)\) with \[ I(g;u)={1\over 2\sqrt\
openaire   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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