Results 81 to 90 of about 1,273,035 (285)

An Integrated Oxygen‐Supplying Device and Predictive Multiphysics Model for Extended Ambient Transport of Insulin‐Producing Cells

Advanced Functional Materials, EarlyView.
Cell therapies typically rely on cold‐chain logistics and cryopreservation, limiting access and compromising cell quality. Here, a dual‐chamber device separates an oxygen‐supplying chamber from a hyaluronic acid cargo chamber, sustaining oxygen delivery for over 70 h and enabling ambient‐temperature shipment.
Daniel A. Domingo‐Lopez, Ruth Tarpey, Benjamin Brennan, Bryan D. Boyle, Amir M. Alsharabasy, Abhik Mallick, Gabriella Bellavia, Abhay Pandit, Garry P. Duffy, Ruth E. Levey   +9 more
wiley   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Architecture‐Driven Functional Coupling in Vertically Aligned Nanocomposites

Advanced Functional Materials, EarlyView.
Vertically aligned nanocomposites define a growth‐engineered architecture in which vertical interfaces, strain fields, defect pathways, and phase connectivity are created simultaneously. This review shows how these architectural features couple ferroic, optical, ionic, electrochemical, and device responses, establishing design rules and open challenges
Md Shatil Islam‐Shanto, Javier Zamudio‐García, Abraham Sánchez‐Caballero, David Marrero‐López, Vincenzo Esposito   +4 more
wiley   +1 more source

Determining source parameters from waveforms of small earthquakes in the Carpathian region of Ukraine

Геофизический журнал, 2018
In the paper, a method is presented for moment tensor inversion of only direct P- and/or S-waves registered at only one station. Lesser sensitivity of direct waves, if compared to reflected and converted waves, to path effects modeling significantly ...
D. V. Malytskyy, A. R. Gnyp, O. D. Hrytsai, O. A. Astashkina, A. Y. Parfeniuk   +4 more
doaj   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

Analysis of Focal Mechanisms Using Waveform Inversion; Case Study of Pidie Jaya Earthquake December 7, 2016

Journal of Aceh Physics Society, 2018
Salah satu gempa bumi yang berdampak pada kerusakan rumah penduduk telah terjadi di Sumatra tepatnya adalah daerah Pidie Jaya pada tanggal 7 Desember 2016, sebesar Mw 6.5.
Qadariyah Qadariah, Andrean VH Simanjuntak, Muksin Umar   +2 more
doaj  

Spatial variation of the present-day strain-rate and stress regime, from mid-Atlantic triple junction through north Africa to Aqaba transform zone

Frontiers in Earth Science
The northern boundary of the African plate is one of the most complex and segmented plate boundary systems worldwide, extending from the Azores Triple Junction in the Mid-Atlantic Ocean to the Gulf of Aqaba in the eastern Mediterranean.
Abdelouahab Issaadi, Farida Ousadou, Samir Aguemoune, Mourad Bezzeghoud, Abdelhakim Ayadi   +4 more
doaj   +1 more source

Mechanism of High Frequency Shallow Earthquake Source in Mount Soputan, North Sulawesi

Indonesian Journal on Geoscience, 2014
DOI: 10.17014/ijog.v6i3.122Moment tensor analysis had been conducted to understand the source mechanism of earthquakes in Soputan Volcano during October - November 2010 period. The record shows shallow earthquakes with frequency about 5 - 9 Hz.
Yasa Suparman, E. Kriswati, Y. E. Pamitro   +2 more
doaj   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source