Results 101 to 110 of about 12,264,579 (389)

Improved sensing characteristics of dual-gate transistor sensor using silicon nanowire arrays defined by nanoimprint lithography

open access: yesScience and Technology of Advanced Materials, 2017
This work describes the construction of a sensitive, stable, and label-free sensor based on a dual-gate field-effect transistor (DG FET), in which uniformly distributed and size-controlled silicon nanowire (SiNW) arrays by nanoimprint lithography act as ...
Cheol-Min Lim   +5 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Distribution Characteristics of Heavy Metals in Soils of the Anhui Section of the Huaihe River Basin

open access: yesYankuang ceshi, 2018
How to scientifically reflect the soil environmental quality of a large area through limited soil point monitoring is a major direction of current research.
QIAN Zhen-bing   +4 more
doaj   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Detecting abundance trends under uncertainty: the influence of budget, observation error and environmental change [PDF]

open access: yes, 2015
ArticleCopyright © 2014 The Authors. Animal Conservation published by John Wiley & Sons Ltd on behalf of The Zoological Society of London.Population monitoring must robustly detect trends over time in a cost-effective manner.
Bunnefeld, N   +2 more
core   +1 more source

"Interactive technology assessment" and beyond: the field trial of genetically modified grapevines at INRA-Colmar. [PDF]

open access: yesPLoS Biology, 2010
Local Monitoring Committee   +3 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Accurate prediction of the 2022 M S 6.9 Menyuan and M S 6.8 Luding earthquake epicentres

open access: yesScientific Reports
In 2022, the M S 6.9 Menyuan (Qinghai Province) and M S 6.8 Luding (Sichuan Province) earthquakes occurred successively on China’s North–South seismic belt.
Yiqing Zhu   +5 more
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Protocol of the SOMNIA project : an observational study to create a neurophysiological database for advanced clinical sleep monitoring [PDF]

open access: yes, 2019
Introduction Polysomnography (PSG) is the primary tool for sleep monitoring and the diagnosis of sleep disorders. Recent advances in signal analysis make it possible to reveal more information from this rich data source.
Arsenali, Bruno   +16 more
core   +2 more sources

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