Results 121 to 130 of about 8,356,133 (342)

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Leak Monitoring

open access: yes, 2017
The efficient use of water resources is a subject of major concern for water utilities and authorities. One of the main challenges in improving the efficiency of drinking-water networks is to minimize water loss in pipes due to leakage. Water leaks in water distribution networks are unavoidable.
Pérez Magrané, Ramon   +4 more
openaire   +4 more sources

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Satellite-Detected Anomalous Changes in Parameters of Various Geophysical Fields During Earthquakes of 6 ≤ M ≤ 7.8 in Türkiye in February 2023

open access: yesRussian Journal of Earth Sciences
Research was conducted using satellite data to study variations in parameters of various geophysical fields manifested in the lithosphere, atmosphere, and ionosphere during the preparation and occurrence of destructive earthquakes of 6 ≤ M ≤ 7.8 in ...
Bondur Valeriy   +6 more
doaj   +1 more source

The Role of executive function in children\u27s source monitoring with varying retrieval strategies [PDF]

open access: yes, 2014
Previous research on the relationship between executive function and source monitoring in young children has been inconclusive, with studies finding conflicting results about whether working memory and inhibitory control are related to source-monitoring ...
Earhart, Becky, Roberts, Kim P.
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

DEVELOPMENT OF THE GRADUATES’ EMPLOYMENT MONITORING SYSTEM

open access: yesВысшее образование в России, 2016
The article suggests a complex approach to the monitoring of graduates’ employment. Analytical materials about employment of graduates of higher education institutions were formed in accordance with the findings of monitoring.
Valery A. Gurtov   +4 more
doaj  

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

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