Results 11 to 20 of about 18,811 (267)
Evaluation of Virulence in Cynomolgus Macaques Using a Virus Preparation Enriched for the Extracellular Form of Monkeypox Virus [PDF]
The 2022 global human monkeypox outbreak emphasizes the importance of maintaining poxvirus research, including enriching a basic understanding of animal models for developing and advancing therapeutics and vaccines.
Eric M. Mucker +10 more
doaj +2 more sources
Monkeypox Virus: Lessons Learnt
The world has been facing a back-to-back hit to life after widespread of viruses since the time of COVID-19. The pandemic had a devastating effect and created history in mankind, but that was not enough for the time.
Sunanda Kulshrestha +2 more
doaj +2 more sources
Ophthalmic manifestations of monkeypox virus [PDF]
Abdelaziz Abdelaal +4 more
openalex +3 more sources
Monkeypox Virus: Epidemiology, Virology, Diagnosis, Vaccine, and Therapeutics. [PDF]
This review provides a comprehensive overview of the latest research advances in MPXV, with a focused analysis across five core dimensions: epidemiology, virology, diagnosis, vaccine, and therapeutics. The primary objective of this review is to advance the understanding of MPXV and facilitate the development of more effective diagnostic methods ...
Yan Y +14 more
europepmc +2 more sources
An mRNA Vaccine Based on Antigens From Conserved Regions of Monkeypox Virus A35R and M1R With a Dimer-Like Conformation Confers Protection Against Both Monkeypox Virus and Vaccinia Virus Infections in Mice. [PDF]
We developed four candidate mRNA vaccine antigens based on conserved sequences of MPXV A35R and M1R proteins. Our findings demonstrate that the MV2 vaccine possesses favorable immunogenicity and prophylactic potential against MPXV and VACV infections, positioning it as a promising clinical candidate for MPXV prevention.
Tang C +14 more
europepmc +2 more sources
Monkeypox Pathogenesis, Transmission, Preventive Measures and Treatment Modalities [PDF]
Monkeypox is a disease transmitted through animals but can also spread from human to human. The causative agent is monkeypox virus which is a ds-DNA virus. Monkeypox virus belongs to the orthopox genus of the poxviridae family.
Vaishnavi Uttam Goradwar, Anil Agrawal
doaj +1 more source
Mechanisms of immune evasion of monkeypox virus
The mpox (disease caused by the monkeypox virus) epidemic in 2022 provides a good opportunity to study the immune response to mpox. Vaccinia virus-infected monocytes could be recognized by monkeypox virus-specific CD4+ and CD8+ T cells, which produce ...
Milad Zandi +4 more
doaj +1 more source
Rapid diagnosis is key to containing viral outbreaks. However, for the current monkeypox outbreak the major deterrent to rapid testing is the requirement for higher biocontainment of potentially infectious monkeypox virus specimens.
Robert J. Fischer +5 more
doaj +1 more source
Due to the rapid evolution of the monkeypox virus, the means by which the monkeypox virus is spread is subject to change. Therefore, the present study aims to analyze the detection of the monkeypox virus according to the collection site of samples from ...
Darwin A. León-Figueroa +7 more
doaj +1 more source

