Results 21 to 30 of about 9,964 (184)

In vitro inhibition of monkeypox virus production and spread by Interferon-β

Virology Journal, 2012
Background The Orthopoxvirus genus contains numerous virus species that are capable of causing disease in humans, including variola virus (the etiological agent of smallpox), monkeypox virus, cowpox virus, and vaccinia virus (the prototypical member of ...
Johnston Sara C, Lin Kenny L, Connor John H, Ruthel Gordon, Goff Arthur, Hensley Lisa E   +5 more
doaj   +1 more source

Tecovirimat as a Potential Bioavailable inhibitor against MPXVgp158 Established through Molecular Dynamic Simulations and Docking Studies

Journal of Pure and Applied Microbiology, 2022
Monkeypox is a zoonotic viral infection caused by monkeypox virus which belongs to the Poxviridae family of genus Orthopoxvirus. Usually, the virus transmission happens when the individual comes in contact with the infected person through body fluids ...
Varruchi Sharma, Anil Panwar, Vivek Kumar Garg, Hardeep Singh Tuli, Sonal Datta, Anil K Sharma, Abhijit Dey, Deepak Chandran, Kuldeep Dhama   +8 more
doaj   +1 more source

The first strain of monkeypox isolated in the Chinese Mainland and preserved at the National Pathogen Resource Center of China

Infectious Medicine, 2022
On September 16, 2022, the first imported monkeypox case was reported in the Chinese Mainland. Laboratory tests including nucleic acid detection were carried out in Chongqing Nan'an Centre for Disease Control and Prevention and Chongqing Center for ...
Qiang Wei, Baoying Huang, Wei Huang, Jingdong Song, Li Mei, Li Zhao, Jing Yin, Juan Zhang, Wenling Wang, Fei Ye, Caiyun Li, Liling Bai, Yanhai Wang, Yao Deng, Bo Liu, Mengnan Jiang, Guizhen Wu, Jun Han, Hua Zhao, Hua Ling, Wenjie Tan, Jianjun Liu   +21 more
doaj   +1 more source

Monkeypox virus: a potential pandemic?

Journal of the Pakistan Medical Association, 2023
Not ...
Daniya, Tarique, Ayesha Ahmed, Siddiqui, Gati, Ara   +2 more
openaire   +2 more sources

Evaluation of Virulence in Cynomolgus Macaques Using a Virus Preparation Enriched for the Extracellular Form of Monkeypox Virus

Viruses, 2022
The 2022 global human monkeypox outbreak emphasizes the importance of maintaining poxvirus research, including enriching a basic understanding of animal models for developing and advancing therapeutics and vaccines.
Eric M. Mucker, Josh D. Shamblin, Arthur J. Goff, Todd M. Bell, Christopher Reed, Nancy A. Twenhafel, Jennifer Chapman, Marc Mattix, Derron Alves, Robert F. Garry, Lisa E. Hensley   +10 more
doaj   +1 more source

Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review

Life, 2023
Monkeypox virus is a double-stranded DNA virus species that causes disease in humans and mammals. It is a zoonotic virus belongs the genus Orthopoxviral, the family of Poxviridae, associated with the smallpox virus in many aspects.
Faheem Anwar, Fatima Haider, Sarmir Khan, Ibrar Ahmad, Naveed Ahmed, Muhammad Imran, Summya Rashid, Zhi-Guang Ren, Saadullah Khattak, Xin-Ying Ji   +9 more
doaj   +1 more source

Immunoinformatic-based design of immune-boosting multiepitope subunit vaccines against monkeypox virus and validation through molecular dynamics and immune simulation

Frontiers in Immunology, 2022
Monkeypox virus is the causative agent of monkeypox disease, belonging to an orthopoxvirus genus, with a disease pattern similar to that of smallpox. The number of monkeypox cases have robustly increased recently in several countries around the world ...
Muhammad Suleman, Farooq Rashid, Shahid Ali, Hassan Sher, Sisi Luo, Sisi Luo, Sisi Luo, Liji Xie, Liji Xie, Liji Xie, Zhixun Xie, Zhixun Xie, Zhixun Xie   +12 more
doaj   +1 more source

Heat inactivation of monkeypox virus

Journal of Biosafety and Biosecurity, 2022
Different kinds of media spiked with monkeypox virus (MPXV) were subjected to heat inactivation at different temperatures for various periods of time. The results showed that MPXV was inactivated in less than 5 min at 70 °C and less than 15 min at 60 °C, with no difference between viruses from the West African and Central African clades.
Batéjat, Christophe, Grassin, Quentin, Feher, Maxence, Hoinard, Damien, Vanhomwegen, Jessica, Manuguerra, Jean-Claude, Leclercq, India   +6 more
openaire   +4 more sources

Proteomic basis of the antibody response to monkeypox virus infection examined in cynomolgus macaques and a comparison to human smallpox vaccination. [PDF]

PLoS ONE, 2010
Monkeypox is a zoonotic viral disease that occurs primarily in Central and West Africa. A recent outbreak in the United States heightened public health concerns for susceptible human populations.
Sarah Keasey, Christine Pugh, Alexander Tikhonov, Gengxin Chen, Barry Schweitzer, Aysegul Nalca, Robert G Ulrich   +6 more
doaj   +1 more source

Monkeypox virus: past and present

World Journal of Pediatrics, 2022
Abstract Background The objective of this paper is to analyze the current status of monkeypox worldwide. In the face of this public health threat, our purpose is to elucidate the clinical characteristics and epidemiology of monkeypox, the developmental progress of monkeypox-related drugs and the vaccines available.
Ya-Mei Dou, Hang Yuan, Hou-Wen Tian
openaire   +2 more sources