Results 121 to 130 of about 10,102 (222)
This study examines MPXV immunity in PLWH, focusing on smallpox vaccine‐induced responses. PLWH with CD4⁺ T‐cell counts <500 cells/mm3 showed reduced VTT‐IgG, MPXV‐IgG, and NAbs, while CD4⁺ T‐cell responses were impaired at counts <350 cells/mm3. CD8⁺ T‐cell responses remained stable.
Qiao Zhang +22 more
wiley +1 more source
Changes in HIV‐1 Reservoir Dynamics After Mpox Infection
ABSTRACT In May 2022, a large outbreak of monkeypox virus (MPXV) occurred in several non‐endemic regions worldwide. Another outbreak in 2024 raised global concerns, particularly for immunocompromised individuals like people with HIV (PWH). Since the latent HIV‐1 reservoir remains a major barrier to a cure, we investigated how past mpox infection ...
Guiomar Casado‐Fernández +14 more
wiley +1 more source
Organoid Models to Study Human Infectious Diseases
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu +4 more
wiley +1 more source
BackgroundHuman monkeypox (MPX) occurs at appreciable rates in the Democratic Republic of Congo (DRC). Infection with varicella zoster virus (VZV) has a similar presentation to that of MPX, and in areas where MPX is endemic these two illnesses are ...
core
Introduction: Monkeypox virus (MPXV), a DNA virus in the genus Orthopoxvirus, causes the clinical disease mpox. Human-to-human transmission occurs, primarily through contact with infectious lesions. The cycle threshold (Ct) value at which mpox virus can be isolated varies in the literature.
Dr Helen Callaby +10 more
openaire +2 more sources
This review combines the current status of CRISPR (Clustered Regularly Interspaced Short Palindromic Repeat)‐based molecular diagnostic technology to expound the necessity and challenges faced in promoting the development of one‐pot detection. Besides, the focus is on a comprehensive summary and incisive analysis of emerging strategies for one‐pot ...
Hongyan Liu +10 more
wiley +1 more source
Large amounts of data and multitudes of publications have been independently generated by researchers in mammalogy and infectious diseases. The frequent confluence of these fields in epidemiological research as well as the facility of the data generated ...
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Clinical Manifestations of an Outbreak of Monkeypox Virus in Captive Chimpanzees in Cameroon, 2016 [PDF]
Monkeypox virus (MPXV) is a re-emerging virus of global concern. An outbreak of Clade I MPXV affected 20 captive chimpanzees in Cameroon in 2016. We describe the epidemiology, virology, phylogenetics, and clinical progression of this outbreak.
Brien, Stephanie C +18 more
core +2 more sources
Characterization of Monkeypox virus infection in African rope squirrels (Funisciurus sp.).
Monkeypox (MPX) is a zoonotic disease endemic in Central and West Africa and is caused by Monkeypox virus (MPXV), the most virulent Orthopoxvirus affecting humans since the eradication of Variola virus (VARV). Many aspects of the MPXV transmission cycle,
Elizabeth A Falendysz +13 more
doaj +1 more source
A REVIEW OF MONKEYPOX DISEASE AND FUTURE TREATMENT OPTIONS [PDF]
The Monkeypox virus (MPXV) causative agent for Monkeypox disease resembles a smallpox-like illness and can lead to a number of serious medical issues in humans.
MISRA, SAURAV, SHUKLA, AJAY KUMAR
core +1 more source

