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Targeting monkeypox virus (MPXV): strategies for molecular docking studies on protein inhibition

Virus Genes
In the year 2022, the outbreak of monkeypox virus (MPXV) occurred in the various countries of Africa, particularly Central and West Africa, North America, South America, Europe, and other countries. Without any delay it spread across more than 100 countries infecting around 116,015 people causing around 255 deaths.
Jayant Murlidhar, Kushwaha   +2 more
openaire   +2 more sources

Structural and Molecular Investigation of the Impact of S30L and D88N Substitutions in G9R Protein on Coupling With E4R From Monkeypox Virus (MPXV)

Journal of Biomolecular Structure and Dynamics
Understanding the pathogenesis mechanism of the Monkeypox virus (MPXV) is essential to guide therapeutic development against the Monkeypox virus. In the current study, we investigated the impact of the only two reported substitutions, S30L, D88N, and S30L-D88N on the G9R of the replication complex in 2022 with E4R using structural modeling, simulation,
Anwar Mohammad, Abbas Khan, Yifan Jin
exaly   +3 more sources

Review of virological methods for laboratory diagnosis and characterization of monkeypox virus (MPXV): lessons learned from the 2022 Mpox outbreak

Acta Dermatovenerologica Alpina Pannonica et Adriatica
Monkeypox virus (MPXV), originally endemic in West Africa (Clade II) and Central Africa (Clade I), has recently emerged worldwide and has reinforced the need for rapid and accurate MPXV diagnostics. This review presents and critically discusses the range of virological methods for laboratory diagnosis and characterization of MPXV as well as related ...
Katarina, Resman Rus   +8 more
openaire   +2 more sources

Construction of Peptide Vaccine Candidate Based on β-Cell Epitopes of Indonesian Monkeypox Virus (MPXV) Virulence Protein:A Reverse Vaccinology

Research Journal of Pharmacy and Technology
Infection with a DNA virus called monkeypox virus (MPXV) in humans has been identified in the Congo since 1970. Antiviral drugs are not effective for preventing MPXV infection. MPXV infection cases in Indonesia are very low but MPXV has the potential to become a global pandemic so it is very important to do prevention such as vaccine development.
Viol Dhea Kharisma   +10 more
openaire   +1 more source

Gestion des prélèvements biologiques d’un patient suspect ou confirmé d’infection par le Monkeypox virus (MPXV)

Revue de biologie médicale, 2022
Sonia Burrel   +11 more
openaire   +1 more source

Evaluation and Validation of an RT-PCR Assay for Specific Detection of Monkeypox Virus (MPXV)

Journal of Medical Virology, 2023
Matthew M Hernandez   +2 more
exaly  

Monkeypox Virus: A Re-Emergent Threat to Humans

Virologica Sinica, 2022
Xia Chuai, Sandra Chiu
exaly  

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