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Risk of Monkeypox Virus (MPXV) Transmission Through the Handling and Consumption of Food

Microbial Risk Analysis, 2022
Monkeypox (MPX) is a zoonotic infectious disease caused by Monkeypox virus (MPXV), an enveloped DNA virus belonging to the Poxviridae family and the Orthopoxvirus genus. Since early May 2022, a growing number of human cases of Monkeypox have been reported in non-endemic countries, with no history of contact with animals imported from endemic and ...
Estelle Chaix, Sandra Martin-Latil
exaly   +5 more sources

Phylogenomic Analysis of the Monkeypox Virus (MPXV) 2022 Outbreak: Emergence of a Novel Viral Lineage?

Travel Medicine and Infectious Disease, 2022
Monkeypox is a zoonotic disease with clinical manifestations similar to smallpox in humans. Since May 13, 2022, an increasing number of suspected and confirmed cases have been reported, affecting non-endemic regions across the globe. More strikingly, reports from the current outbreak reveal unique aspects regarding transmission dynamics and an ...
Juan D Ramírez, Marina Muñoz, D Katterine Bonilla-Aldana   +2 more
exaly   +3 more sources

Monkeypox Virus (MPXV): A Brief Account of Global Spread, Epidemiology, Virology, Clinical Features, Pathogenesis, and Therapeutic Interventions

Infectious Medicine, 2023
حدث أكبر تفشي لفيروس MPXV في القرن الحادي والعشرين في عام 2022، مما تسبب في أوبئة في العديد من البلدان. وفقًا لمنظمة الصحة العالمية، قد يكون الاتصال الجسدي مع الأشخاص المصابين أو الأسطح الملوثة أو الحيوانات المصابة مصدرًا لانتقال الفيروس. مرض حموي بما في ذلك بعض الأعراض الموجودة في مرض إم بي إكس.
Ahrar Khan, Md Atiqul Haque, Md Azizul Haque   +2 more
exaly   +4 more sources

Monkeypox Virus (MPXV)

World Journal of Advanced Research and Reviews, 2022
Monkeypox (MPXV) is a zoonosis with a double-origin DNA (DNA), caused by monkeypox virus, an orthopox virus and close relative of variola virus (smallpox). It was first reported in central Africa in 1970 and has historically affected some of the poorest and most marginalized communities in the world.
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An Immunoinformatic Approach Towards Development of a Potent and Effective Multi-Epitope Vaccine Against Monkeypox Virus (MPXV)

Journal of Biomolecular Structure and Dynamics, 2023
Monkeypox is a viral zoonotic disease, often transmitted to humans from animals. While the whole world is haggling with the COVID-19 pandemic, the emergence of the monkeypox virus (MPXV) arose as a new challenge to mankind. Till date, numerous cases related to the MPXV have been reported in several countries across the globe, but, its momentary ...
Sanghamitra Pati, Budheswar Dehury, Sunita Panda   +2 more
exaly   +3 more sources

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Monkeypox Virus (MPXV) Infection: A Review

Infectious Disorders - Drug Targets
Abstract: Monkeypox is a viral disease; its outbreak was recently declared a global emergency by the World Health Organization. For the first time, a monkeypox virus (MPXV)-infected patient was found in India. Various researchers back-to-back tried to find the solution to this health emergency just after COVID-19.
Jay Parkash Yadav, Ratish Chandra Mishra
exaly   +3 more sources

Proteomics-Based Vaccine Targets Annotation and Design of Subunit and mRNA-Based Vaccines for Monkeypox Virus (MPXV) Against the Recent Outbreak

Computers in Biology and Medicine, 2023
Monkeypox Virus (MPXV) is a growing public health threat with increasing cases and fatalities globally. To date, no specific vaccine or small molecule therapeutic choices are available for the treatment of MPXV disease. In this work, we employed proteomics and structural vaccinology approaches to design mRNA and multi-epitopes-based vaccines (MVC ...
Yanjing Wang, Abbas Khan, Yifan Jin
exaly   +4 more sources

Ocular Manifestations of Monkeypox Virus (MPXV) Infection With Viral Persistence in Ocular Samples: A Case Series

International Journal of Infectious Diseases
We describe the clinical presentation and ocular viral dynamics in patients with Monkeypox virus-related ophthalmic disease (MPXROD).In this case series, we investigated five consecutive patients with confirmed mpox, diagnosed through a positive Monkeypox virus (MPXV) Polymerase Chain Reaction (PCR) test and presenting with ocular symptoms.
Dalton de Freitas Santoro, Guilherme Macedo Souza, Steven S Witkin   +2 more
exaly   +4 more sources

Defining antigen targets to dissect vaccinia virus (VACV) and Monkeypox virus (MPXV)-specific T cell responses in humans

2022
Abstract The current Monkeypox virus (MPXV) outbreak in non-endemic countries is raising concern about the pandemic potential of novel orthopoxviruses. Little is known regarding MPXV immunity in the context of MPXV infection or vaccination with Vaccinia-based vaccines (VACV).
Alba Grifoni, Yun Zhang, Alison Tarke, John Sidney, Paul Rubiro, Maria Reina-Campos, Gilberto Filaci, Jennifer Dan, Richard H. Scheuermann, Alessandro Sette   +9 more
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Multi-Center Evaluation of the Research Use Only NeuMoDx Monkeypox Virus (MPXV) Fully Automated Real-Time PCR Assay.

Journal of Clinical Microbiology
ABSTRACT The mpox outbreak, caused by monkeypox virus (MPXV), accelerated the development of molecular diagnostics. In this study, we detail the evaluation of the Research Use Only (RUO) NeuMoDx MPXV assay by multiple European and US sites. The assay was designed and developed by Qiagen for the NeuMoDx
Federico Garcia, Heba H Mostafa, Elizaveta Padalko   +2 more
exaly   +5 more sources