Results 91 to 100 of about 1,041,172 (171)

Organoids: From Bench to Bedside Applications

MedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li, Rui Cao, Maochen Li, Zichao Tian, Huahao Fan, Bixia Hong, Xiaojuan Liu   +6 more
wiley   +1 more source

Thermodynamics and Conformational Dynamics of Primer Nucleotide Sequences Associated with Monkeypox Virus (MpxV): Comparative Analysis of Stability and Specificity with a Biophysical-Computational Approach

Biointerface Research in Applied Chemistry, 2023
COVID-19 pandemic has shown the need to detect new pathogens quickly. Currently, attention has been paid to the recent epidemic of the Monkeypox virus (MpxV), the etiological agent of the zoonotic disease monkeypox. As happened with COVID-19, diagnosis is the priority in public health interventions.
openaire   +1 more source

Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Sola Akinbolade, Rhiannon Potter, Alex Inskip, Jane Nesworthy, Kirsti Brock, Gill Norman   +5 more
wiley   +1 more source

Machine Learning‐Augmented Loop‐Mediated Isothermal Amplification‐Enabled Point‐of‐Care for Mpox‐Specific Detection

Advanced Intelligent Systems, Volume 8, Issue 5, May 2026.
A low‐cost, portable point‐of‐care platform for rapid Mpox detection using loop‐mediated isothermal amplification is reported. The device integrates fluorescence readout and mobile monitoring. A machine‐learning model analyzes temperature data and correlates thermal changes with DNA concentration, enabling sensitive and reliable molecular diagnosis in ...
Nazente Atceken, Ahmed Choukri Abdullah, Olgac Ozarslan, Ziya Yıldız, Savas Tasoglu   +4 more
wiley   +1 more source

Readiness Level of Spanish Labs to Detect Mpox Clade Ib: A Nationwide EQA

Journal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT To assess the preparedness and diagnostic capacity of Spanish clinical microbiology laboratories to detect the emerging monkeypox virus (MPXV) Clade Ib through a nationwide external quality assessment. A blinded 16‐sample panel (serum and DNA eluates) containing MPXV Clade Ib, Clade II, vaccinia, and negatives was distributed.
Adolfo De Salazar, Anabel Negredo, Juan Carlos Galán, Teresa Del Peso, Marta Illescas, Laura Martínez‐García, Concepción Gimeno, Federico García, María Paz Sánchez‐Seco, the QC Mpox Spain Collaborators, Sonia Algarate, Andrés Antón, Ana Milagro, Fernando Buñuel, Laura Calatayud, Pilar Catalán, Gregorio Marañón, Marta Domínguez‐Gil González, Manel Flores, Pablo Fraile, Ana Fuentes López, María del Carmen Garma, Mª Dolores Gómez‐Ruíz, Mónica Gozalo, Manuel Grau, Almudena Gutiérrez‐Arroyo, Silvia Hernáez, Águeda Hernández‐Rodríguez, Noelia Hernando, Flor Isabel Hidalgo, José Luis Juan, Eduardo Lagarejos, Miguel Julián Martínez‐Yoldi, Santiago Melón, Pablo Mendoza, Laura Merino, Milagrosa Montes, Jordi Niubó, María Dolores Ocete, Alejandra Pérez‐García, Jorge Alfredo Pérez‐García, Mercedes Pérez‐Ruiz, Sonia Pérez‐Castro, Jordi Reina, Romina Soledad Romero, Genoveva Santillana, Encarna Simarro, Mikel Urruticoechea, Laura Herrero, Francisca Molero   +49 more
wiley   +1 more source

Evolution of Point‐of‐Care Nucleic Acid Testing: From Amplification Chemistry to Intelligent and Data‐Driven Systems for Public Health

Aggregate, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in integrated point‐of‐care testing (POCT) systems for public health, encompassing isothermal nucleic acid amplification, CRISPR‐based signal amplification, device integration, and chemometric/artificial intelligence‐assisted data interpretation, with applications in infectious disease surveillance, food and ...
Yan Du, Jiaqi Li, Jinghong Li
wiley   +1 more source

Protective efficacy of a genetically modified attenuated vaccinia virus Tiantan strain against monkeypox virus challenge in a small animal model

Journal of Virology
Vaccinia virus (VACV) confers cross-protective immunity against monkeypox virus (MPXV), the causative agent of mpox, and has therefore been extensively exploited as a preventive vaccine.
Wenhao Su, Tingting Zhao, Xiuxiu Ren, Shishi Li, Qiufang Huang, Jingjing Liu, Xiaohuan Zhang, Zihao Ge, Jiangbo Wei   +8 more
doaj   +1 more source

Occupational Monkeypox Virus Transmission to Healthcare Worker, California, USA, 2022

, 2023
Risk for transmission of monkeypox virus (MPXV) (clade IIb) to healthcare workers (HCWs) is low. Although many cases have been reported among HCW, only a few have been occupationally acquired.
Annette Guerrero, McKailey Walters, Jemma Alarcón, Sharon E. Balter, Moon Kim, Abraar Karan, Francisca Mata, Dawn Terashita, Lauren E. Finn, Nora Balanji, Anissa Davis   +10 more
core   +1 more source

Monkeypox virus transmission in tattoo parlor

, 2023
In monkeypox virus (MPXV) transmission caused by contaminated material, we have to consider that recently the outbreak of several MPXV cases was linked to tattoo parlors in Cadiz, Spain.
Geminiani M., Giuliano S., Pagotto A., Tascini C., Sbrana F.   +4 more
core   +1 more source

Characterization of Monkeypox virus infection in African rope squirrels (Funisciurus sp.).

PLoS Neglected Tropical Diseases, 2017
Monkeypox (MPX) is a zoonotic disease endemic in Central and West Africa and is caused by Monkeypox virus (MPXV), the most virulent Orthopoxvirus affecting humans since the eradication of Variola virus (VARV). Many aspects of the MPXV transmission cycle,
Elizabeth A Falendysz, Juan G Lopera, Jeffrey B Doty, Yoshinori Nakazawa, Colleen Crill, Faye Lorenzsonn, Lem's N Kalemba, Monica D Ronderos, Andres Mejia, Jean M Malekani, Kevin Karem, Darin S Carroll, Jorge E Osorio, Tonie E Rocke   +13 more
doaj   +1 more source