Results 71 to 80 of about 699 (118)

Antifolate agent aminopterin demonstrates potent anti-monkeypox virus activity in vitro and in vivo

Microbiology Spectrum
The ongoing spread of the monkeypox outbreak underscores the urgent need for the development of effective therapeutics against the monkeypox virus (MPXV).
Jing Wu, Meimei Duan, Lin Cheng, Deyan Chen   +3 more
doaj   +1 more source

Characterization of Monkeypox virus infection in African rope squirrels (Funisciurus sp.).

PLoS Neglected Tropical Diseases, 2017
Monkeypox (MPX) is a zoonotic disease endemic in Central and West Africa and is caused by Monkeypox virus (MPXV), the most virulent Orthopoxvirus affecting humans since the eradication of Variola virus (VARV). Many aspects of the MPXV transmission cycle,
Elizabeth A Falendysz, Juan G Lopera, Jeffrey B Doty, Yoshinori Nakazawa, Colleen Crill, Faye Lorenzsonn, Lem's N Kalemba, Monica D Ronderos, Andres Mejia, Jean M Malekani, Kevin Karem, Darin S Carroll, Jorge E Osorio, Tonie E Rocke   +13 more
doaj   +1 more source

Epidemiology of Human Monkeypox about the 2022 Outbreak: A Narrative Review [PDF]

Journal of Community Health Research
:  Human Monkeypox is a zoonotic disease caused by 2 distinct clades of human monkeypox virus (MPXV). MPXV infections can cause several clinical symptoms including fever, skin rash, back pain, and lymphadenopathy in humans.
Aliasghar Fakhri-Demeshghieh, Hesameddin Akbarein, Parsa Almasi   +2 more
doaj  

Metallo-supramolecular complexes enantioselectively target monkeypox virus RNA G-quadruplex and bolster immune responses against MPXV

National Science Review
ABSTRACT The Mpox virus (MPXV) has emerged as a formidable orthopoxvirus, posing an immense challenge to global public health. An understanding of the regulatory mechanisms of MPXV infection, replication and immune evasion will benefit the development of novel antiviral strategies.
Jie Yang, Geng Qin, Baoying Huang, Hualong Song, Jiewei Sun, Miles Postings, Peter Scott, Chuanqi Zhao, Chunyu Wang, Wenjie Tan, Jinsong Ren, Xiaogang Qu   +11 more
openaire   +2 more sources

Abstract Supplement HIV Glasgow 8–11 November 2026, Glasgow, UK/Virtual

Journal of the International AIDS Society, Volume 29, Issue S6, November 2026.
wiley   +1 more source

An Ensemble Fuzzy-MCDM Approach for Evaluation of Approved Monkeypox Vaccines

The EuroBiotech Journal
Objective: Monkeypox, a disease caused by a deoxyribonucleic acid (DNA) based virus (MPXV) has posed global health challenges to the entire populace.
Usanase Natacha, Emegano Declan Ikechukwu, Uzun Berna, Ozsahin Dilber Uzun, Ozsahin Ilker   +4 more
doaj   +1 more source

A comprehensive review of monkeypox virus and mpox characteristics

Frontiers in Cellular and Infection Microbiology
Monkeypox virus (MPXV) is the etiological agent of monkeypox (mpox), a zoonotic disease. MPXV is endemic in the forested regions of West and Central Africa, but the virus has recently spread globally, causing outbreaks in multiple non-endemic countries ...
Emmanuel Alakunle, Daniel Kolawole, Diana Diaz-Cánova, Faith Alele, Oyelola Adegboye, Ugo Moens, Malachy Ifeanyi Okeke   +6 more
doaj   +1 more source

Transmissibility of Clade IIb Monkeypox Virus in Young Rabbits

Microorganisms
The monkeypox virus (MPXV) has spread globally, posing a severe challenge to global public health. This study systematically evaluated the aerosol shedding dynamics of the epidemic Clade IIb MPXV strain in infected young rabbits, along with its direct ...
Zhaoliang Chen, Lei Zhang, Linzhi Li, Mingjie Shao, Mingda Zhang, Zongzheng Zhao, Chao Shang, Zirui Liu, Juxiang Liu, Zhendong Guo   +9 more
doaj   +1 more source

Rapid regional mobile laboratory response and genomic monkeypox virus (MPXV) surveillance in seven East African Community partner states, August 2024: preparedness activities for the ongoing outbreak

Eurosurveillance
The East African Community (EAC) is experiencing an unprecedented, emerging mpox outbreak since July 2024 in five of eight partner states. We highlight rapid regional response measures, initiated August 2024 coordinated by EAC: field deployment of six mobile laboratories in Burundi, Rwanda, Uganda, Tanzania, Kenya, South Sudan to high-risk areas ...
Florian Gehre, Eric Nzeyimana, Hakim Idris Lagu, Emmanuel Achol, Julien A Nguinkal, Eric Kezakarayagwa, Théogene Ihorimbere, Néhémie Nzoyikorera, Francine Kabatesi, Marie-Noelle Uwineza, Abdi Roba, Millicent Nyakio Ndia, John Ndemi Kiiru, Gwokpan Awin Nykwec, Isaac Gatkuoth Chot Moun, Mamdouh A Aguer, James A Maror, Gregory Wani Dumo, Michael Losuba, Lul Lojok Deng, Neema Omari, Grace Ochido, Aryse Martins Melo, Peter Bernard Mtesigwa Mkama, Edna Mgimba, Monica Fredrick Francis, Lawrence A Mapunda, Alex Magesa, Nyambura Moremi, Godfrey Pimundu, Tonny Muyigi, Susan Ndidde Nabadda, Emmanuel Kabalisa, Isabelle Mukagatare, Daniel Mukadi-Bamuleka, Erick Ntambwe Kamangu, Jürgen May, Muna Affara   +37 more
openaire   +2 more sources

Investigating seroprevalence of IgG antibodies against Monkeypox Virus (MPXV) in a cohort of people living with HIV (PLWH) in Rome, during the 2022 outbreak: Moving beyond traditional at-risk populations

Travel Medicine and Infectious Disease
High incidence mpox rates suggest asymptomatic individuals may contribute to virus transmission. We undertook this study to assess the seroprevalence of IgG anti-MPXV in a cohort of asymptomatic PLWH, to analyze the size of the phenomenon of asymptomatic infections.From October 2022 to March 2023 we serially collected serum samples from PLWH attending ...
Salvo, Pierluigi Francesco, Sanfilippo, Alessia, Baldin, Gianmaria, Iannone, Valentina, Ciccullo, Arturo, Farinacci, Damiano, Benvenuto, Domenico, Borghetti, Alberto, Di Giambenedetto, Simona, Lombardi, Francesca   +9 more
openaire   +3 more sources