Results 51 to 60 of about 699 (118)
Diagnostic approaches for monkeypox virus
Mpox (formerly Monkeypox) is a zoonotic infection caused by Monkeypox virus (MPXV). Since 2022, Mpox epidemics have occurred in many non‐endemic countries and regions, leading the World Health Organization to declare a public health emergency of ...
Guohao Fan +5 more
doaj +1 more source
Monkeypox: Uma zoonose de preocupação mundial
A monkeypox é uma doença zoonótica de origem africana, causada pelo vírus monkeypox (MPXV), pertencente à família Poxviridae. Inicialmente descoberto na década de 1958, o surto registrado em 2022 compreende a doença em sua maior distribuição mundial ...
Ana Carolina Leal da Cruz Lisboa +3 more
doaj +1 more source
History of sexually transmitted infections among mpox cases in the 2022 outbreak in Spain
Abstract Objective The aim was to describe the history of sexually transmitted infections (STIs) among adult mpox men cases and to analyse sociodemographic and epidemiological characteristics according to the presence or absence of any STI diagnosed 1 or 6 months previous to mpox diagnosis during the 2022 outbreak in Spain.
Aina March‐Yagüe +35 more
wiley +1 more source
Monkeypox (mpox) is the most significant orthopoxvirus (OPXV) infection in humans since smallpox eradication. The World Health Organization (WHO) has twice declared public health emergency of international concern due to the expansive spread of clade I ...
Shanshan Li +13 more
doaj +1 more source
Identification of Repurposed Drugs Against Monkeypox Virus Through Comprehensive Virtual Screening
Graphical Abstract and Lay Summary By combining interspecies protein analysis with advanced virtual screening, this study identifies potent repurposed drug candidates—including vindesine and LY2090314—targeting mpox DNA topoisomerase and polymerase. This workflow provides a rapid, practical framework for antiviral discovery against emerging infectious ...
Taeho Yu, Woo Dae Jang, Sang Yup Lee
wiley +1 more source
Severe Scrotal Cellulitis in a Young Man
JEADV Clinical Practice, EarlyView.
Hamad El Hajj +3 more
wiley +1 more source
This study employs an in silico virtual screening workflow to evaluate lactic acid bacteria (LAB)‐derived bacteriocins as potential inhibitors of the monkeypox virus DNA polymerase (MPDP). Protein‐peptide docking simulations using the HADDOCK platform revealed that Sakacin P and Mundticin KS possess the highest binding affinities for the MPDP target ...
Melisa Z. Karaman +6 more
wiley +1 more source
ABSTRACT Background HIV causes immunosuppression by targeting CD4+ T lymphocytes, which may influence susceptibility and clinical outcomes of coinfections such as the Mpox virus (MPXV). Despite conflicting evidence, understanding the relationship between CD4 counts and MPXV severity in people living with HIV (PLWH) remains critical.
Kesaobaka Batisani +21 more
wiley +1 more source
High‐affinity monoclonal antibodies (mAbs) targeting the MPXV EEV protein A35R were rapidly isolated using mRNA‐LNP vaccination and the Beacon single‐cell sorting Optofluidic platform, followed by functional profiling. One mAb, 17H1, potently neutralized authentic MPXV and conferred complete protection in vivo.
Shimeng Bai +10 more
wiley +1 more source
There is no effective method to treat this virus and prevent its transmission. To address this, we have developed a nano‐silver‐selenium liquid dressing (AgSe@LD) by combining silver and selenium nanoparticles with commercial liquid dressings. This unique AgSe@LD formulation exhibits good adhesion, stability and toughness and demonstrates efficient ...
Wei Wang +15 more
wiley +1 more source

