Results 61 to 70 of about 1,041,172 (171)

From actually toxic to highly specific – novel drugs against poxviruses [PDF]

, 2007
The potential use of variola virus, the causative agent of smallpox, as a bioweapon and the endemic presence of monkeypox virus in Africa demonstrate the need for better therapies for orthopoxvirus infections. Chemotherapeutic approaches to control viral
Schnierle Barbara, Sliva Katja, Sliva, Katja, Schnierle, Barbara   +3 more
core   +1 more source

Cross-reactive immune responses to monkeypox virus induced by MVA vaccination in mice

Virology Journal, 2023
Mpox (monkeypox) infection cases increased recently in non-Mpox outbreak areas, potentially causing an international threat. The desire to defend against a potential outbreak has led to renewed efforts to develop Mpox vaccines.
Feixia Gao, Cheng He, Min Liu, Ping Yuan, Shihua Tian, Mei Zheng, Linya Zhang, Xu Zhou, Fangjingwei Xu, Jian Luo, Xiuling Li   +10 more
doaj   +1 more source

Monkeypox virus: The changing facets of a zoonotic pathogen [PDF]

, 2022
In the last five years, the prevalence of monkeypox has been increasing both in the regions considered endemic for the disease (West and Central Africa) and worldwide.
Forni, Diego, Molteni, Cristian, Cagliani, Rachele, Clerici, Mario, Sironi, Manuela   +4 more
core   +1 more source

Monkeypox Virus Transmission to Healthcare Worker through Needlestick Injury, Brazil

Emerging Infectious Diseases, 2022
We describe monkeypox virus (MPXV) transmission from a patient to a healthcare worker through needlestick injury. A lesion appeared at the inoculation site 5 days after injury.
Laína Bubach Carvalho, Luciana V.B. Casadio, Matheus Polly, Ana Catharina Nastri, Anna Cláudia Turdo, Raissa H. de Araujo Eliodoro, Ester Cerdeira Sabino, Anna Sara Levin, Adriana Coracini Tonacio de Proença, Hermes Ryoiti Higashino   +9 more
doaj   +1 more source

Viruela del simio: ¿estamos frente a un riesgo de pandemia?. Historia de un viejo conocido

Interdisciplinary Journal of Epidemiology and Public Health, 2022
La viruela del simio es una zoonosis de etiología viral causada por virus de la viruela del simio o Monkeypox virus (MPXV) (por su nombre en inglés). MPXV es un virus de ADN de doble cadena de la familia Poxviridae, a la cual pertenece el virus Variola ...
Richar Jose Gomez De la Rosa, Juan Pablo Rojas   +1 more
doaj   +1 more source

Biological characteristics, biosafety prevention and control strategies for the 2022 multi-country outbreak of monkeypox

Biosafety and Health, 2022
Monkeypox is a zoonotic disease caused by the monkeypox virus (MPXV), which is a potential biological warfare agent of bioterrorism and poses the greatest threat to the world’s public biosafety and health after variola virus (VARV). While the coronavirus
Chudan Liang, Jun Qian, Linna Liu
doaj   +1 more source

A Comparative Evaluation of Three Diagnostic Assays for the Detection of Human Monkeypox

Viruses
Accurate and early diagnosis of monkeypox virus (MPXV) is crucial for controlling epidemics and treating affected individuals promptly. This study aimed to assess the analytical and clinical performance of the MolecisionTM Monkeypox Virus qPCR Assay ...
Jing Qu, Xiaomin Zhang, Kun Liu, You Li, Ting Wang, Zhonggang Fang, Cheng Chen, Xiao Tan, Ying Lin, Qing Xu, Yan Yang, Wanqing Wang, Manyu Huang, Shiliang Guo, Ziqiu Chen, Wei Rao, Xiaolu Shi, Bo Peng   +17 more
doaj   +1 more source

Prevention, Vaccination, Management and Infection Control of Monkeypox Outbreak: an Update Global Recommendation for the Next Year 2023

Journal of Pure and Applied Microbiology, 2022
A sudden increase in human monkeypox infections that began in non-endemic nations in May 2022 has sparked concerns about a new global infectious threat. The number of people who are vulnerable to infection with MPXV is growing worldwide. On July 23, 2022,
Sirwan Khalid Ahmed
doaj   +1 more source

Efficient Inactivation of Monkeypox Virus by World Health Organization‒Recommended Hand Rub Formulations and Alcohols

Emerging Infectious Diseases, 2023
Increasing nonzoonotic human monkeypox virus (MPXV) infections urge reevaluation of inactivation strategies. We demonstrate efficient inactivation of MPXV by 2 World Health Organization‒recommended alcohol-based hand rub solutions.
Toni L. Meister, Ronny Tao, Yannick Brüggemann, Daniel Todt, Joerg Steinmann, Joerg Timm, Ingo Drexler, Eike Steinmann   +7 more
doaj   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source