Results 141 to 150 of about 10,102 (222)

International external quality assessment study for detection of monkeypox virus by PCR supporting laboratory preparedness during the 2022-2023 mpox outbreak and beyond [PDF]

BACKGROUND: Diagnostic capabilities and correspondent External Quality Assessments (EQA) are key for outbreak preparedness. To support diagnostic facilities with a quality assessment of newly established monkeypox virus (MPXV) molecular diagnostic ...
Bugert, Joachim J, Donoso Mantke, Oliver, Ehmann, Rosina, McCulloch, Elaine, Niesters, Hubert G M, Ricketts, Alastair, Staines, Harry, Wölfel, Roman, Yousef, Amani   +8 more
core   +1 more source

Ongoing mpox outbreak in Kamituga, South Kivu province, associated with monkeypox virus of a novel Clade I sub-lineage, Democratic Republic of the Congo, 2024

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Since the beginning of 2023, the number of people with suspected monkeypox virus (MPXV) infection have sharply increased in the Democratic Republic of the Congo (DRC). We report near-to-complete MPXV genome sequences derived from six cases from the South
Leandre Murhula Masirika, J. C. Udahemuka, L. Schuele, Pacifique Ndishimye, Saria Otani, Justin Bengehya Mbiribindi, Jean M Marekani, L. M. Mambo, Nadine Malyamungu Bubala, M. Boter, David F. Nieuwenhuijse, Trudie Lang, E. Kalalizi, J. Musabyimana, F. Aarestrup, M. Koopmans, B. O. Oude Munnink, Freddy Belesi Siangoli   +17 more
semanticscholar   +1 more source

Is monkeypox virus (MPXV) older than we think?

Transboundary and Emerging Diseases, 2022
AbdulRahman A. Saied
semanticscholar   +1 more source

First Clade Ib Monkeypox Virus Infection Reported in the Americas — California, November 2024

MMWR. Morbidity and mortality weekly report
A clade I monkeypox virus (MPXV) outbreak is ongoing in the Democratic Republic of the Congo; travel-associated clade I MPXV infections have been reported in non-African countries.
V. Levy, Anna Branzuela, Kristina Hsieh, Shiffen Getabecha, Ricardo Berumen, Kayla Saadeh, Robert E. Snyder, G. Marek, Daniel Dodson, Alyssa Newman, Jill K. Hacker, Chantha Kath, F. S. Minhaj, C. Gigante, S. Gearhart, Alexander Kallen, Christina L. Hutson, Kathleen Jacobson, Robert Avina, Josh Bunao, Jahara Cayabyab, Edwin Chojolan, E. Epson, A. Espinosa, Bianca Gonzaga, Monica Haw, Kelly A Johnson, Awa Keinde, Deidra Lemoine, Kelsey Maccuish, A. Mcgonagle, Rilene Ng, R. Piper, Will S Probert, Maria Salas, Brandon Stavig, Juliet Stoltey, Orlanda Tafolla, Eric C. Tang, D. Wadford, Jessica Watson, V. Wong, Ermias Belay, Shama Cash-Goldwasser, W. Davidson, Jiusheng Deng, Marie A. de Perio, A. Gertz, David W. Hunter, Aaron D Kofman, R. Lash, Andrea M. McCollum, A.D. McNaghten, Agam K Rao, P. Satheshkumar, Emily Sims, Ian T. Williams, Italo B. Zecca   +57 more
semanticscholar   +1 more source

The Generation and Characterization of Monoclonal Antibodies against the MPXV A29L Protein

Viruses
Mpox (formerly known as monkeypox) is a zoonotic disease caused by monkeypox virus (MPXV), a DNA virus belonging to the Orthopoxvirus genus, in the Poxviridae family. The disease constitutes a moderate risk to public health at the global level.
Wenlong Zhu, Mengjia Zhang, Mengdi Zhang, Ran Jing, Jiaru Zhou, Hua Cao, Changcheng Liu, Hongmei Zhu, Ahmed H. Ghonaim, Sherin R. Rouby, Wentao Li   +10 more
doaj   +1 more source

Clinical manifestations and pathogenicity of Clade IIb monkeypox virus in rabbits

Emerging Microbes and Infections
The 2022 monkeypox outbreak involved rapid global dissemination, prompting research into animal models for the monkeypox virus (MPXV), including non-human primates and mice. However, studies utilizing rabbits as models remain limited.
Chao Shang, Shaowen Shi, Qiwei Jiang, Xiaohan Wang, Xiaohong Yao, Wanzi Li, Gaojie Song, Yiquan Li, Yongyang Sun, Jinglei Hu, Cuiling Zhang, Yilong Zhu, Zirui Liu, Chaode Gu, Yan Liu, Wanyu Shi, Zongzheng Zhao, Xiao Li   +17 more
semanticscholar   +1 more source

Clade I Monkeypox virus genomic diversity in the Democratic Republic of the Congo, 2018 - 2024: Predominance of Zoonotic Transmission

medRxiv
Background: Recent reports raise concerns on the changing epidemiology of mpox in the Democratic Republic of the Congo (DRC), with increasing case counts, sexual contact-mediated clusters, and sustained human-to-human transmission driven by a novel ...
E. Kinganda-Lusamaki, A. Amuri-Aziza, Nicolas Fernandez-Nuñez, J. Makangara-Cigolo, Catherine Pratt, E. Vakaniaki, N. Hoff, Gradi Luakanda-Ndelemo, P. Akil-Bandali, Sabin S Nundu, N. Mulopo-Mukanya, Michel Ngimba, Brigitte Modadra-Madakpa, Ruth Diavita, Princesse Paku-Tshambu, E. Pukuta-Simbu, Sydney Merritt, Á. O'toole, N. Low, A. Nkuba-Ndaye, H. Kavunga-Membo, Robert Shongo Lushima, Laurens Liesenborghs, T. Wawina-Bokalanga, K. Vercauteren, D. Mukadi-Bamuleka, L. Subissi, J. Muyembe‐Tamfum, J. Kindrachuk, A. Ayouba, A. Rambaut, Eric Delaporte, S. Tessema, Eric D’Ortenzio, Anne W Rimoin, Lisa E Hensley, P. Mbala-Kingebeni, M. Peeters, S. Ahuka-Mundeke   +38 more
semanticscholar   +1 more source

Insights into the Transmission, Host Range, Genomics, Vaccination, and Current Epidemiology of the Monkeypox Virus

Veterinary Medicine International
This review delves into the historical context, current epidemiological landscape, genomics, and pathobiology of monkeypox virus (MPXV). Furthermore, it elucidates the present vaccination status and strategies to curb the spread of monkeypox.
Yusha Araf, Jannatul Ferdous Nipa, Sabekun Naher, Sumaiya Tasnim Maliha, Hasanur Rahman, Kazi Ifthi Arafat, Mohammad Raguib Munif, Md Jamal Uddin, Nurejunnati Jeba, Sukumar Saha, Jingbo Zhai, S. M. Nazmul Hasan, Mengzhou Xue, Md. Golzar Hossain, Chunfu Zheng   +14 more
doaj   +1 more source

Ultrasensitive single-step CRISPR detection of monkeypox virus in minutes with a vest-pocket diagnostic device

Nature Communications
The emerging monkeypox virus (MPXV) has raised global health concern, thereby highlighting the need for rapid, sensitive, and easy-to-use diagnostics. Here, we develop a single-step CRISPR-based diagnostic platform, termed SCOPE (Streamlined CRISPR On ...
Yunxiang Wang, Hong Chen, Kai Lin, Yongjun Han, Zhixia Gu, Hongjuan Wei, Kai Mu, Dongfeng Wang, Liyan Liu, Ronghua Jin, Rui Song, Zhen Rong, Shengqi Wang   +12 more
semanticscholar   +1 more source

Establishment of an animal model for monkeypox virus infection in dormice

Scientific Reports
This study aims to establish an animal model of monkeypox virus (MPXV) infection in dormice through intranasal inoculation. Male dormice aged 4–5 months were selected as experimental subjects and administered different titers of MPXV (103.5 PFU, 104.5 ...
Gaojie Song, Lingling Cheng, Jun Liu, Yu Zhou, Cuiling Zhang, Yuping Zong   +5 more
doaj   +1 more source