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Ultrasonic vocalizations as a predictor of resilience to intermittent swim stress-induced anxiety: An investigation of re-exposure effects [PDF]
, 2016 Drugan, Robert C +2 more
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Monoamine Oxidase B Inhibitors in Parkinson's Disease.
CNS & Neurological Disorders - Drug Targets, 2017Parkinson's disease (PD) is a neurodegenerative disorder with a prevalence increasing with age. Oxidative stress and glutamate toxicity are involved in its pathomechanism. There are still many unmet needs of PD patients, including the alleviation of motor fluctuations and dyskinesias, and the development of therapies with neuroprotective potential.To ...
L. Dézsi, L. Vécsei
semanticscholar +4 more sources
Analytical Chemistry, 2021
Liver fibrosis could induce cirrhosis and liver cancer, causing serious damages to liver function and even death. Early diagnosis of fibrosis is extremely requisite for optimizing treatment schedule to improve cure rate.
Nannan Fan +6 more
semanticscholar +1 more source
Liver fibrosis could induce cirrhosis and liver cancer, causing serious damages to liver function and even death. Early diagnosis of fibrosis is extremely requisite for optimizing treatment schedule to improve cure rate.
Nannan Fan +6 more
semanticscholar +1 more source
Crystallization of Human Monoamine Oxidase B
2022The interest in monoamine oxidases A and B (MAO A and B) is due to their central role in regulating the balance of neurotransmitters, both in the central nervous system and in peripheral organs. As validated drug targets for depression and Parkinson's disease, the elucidation of their crystal structures was an essential step to guide drug design ...
Binda, Claudia +2 more
openaire +3 more sources
Monoamine oxidase‐B in astrocytes
Glia, 1993AbstractIn the present report we describe the astrocytic localization and content of monoamine oxidase‐B (MAO‐B) by means of a 3H‐L‐deprenyl emulsion autoradiography in primary cultures of rat astrocytes, in cryosectioned astrocytoma surgical specimen, and in cryosections of human spinal cords from patients dying in amyotrophic lateral sclerosis (ALS ...
J, Ekblom +5 more
openaire +2 more sources
PET Imaging of Monoamine Oxidase B
, 2020The monoamine oxidase B (MAO-B) enzyme has a prominent role in brain function, being involved in the breakdown of monoaminergic neurotransmitters. Abnormally high MAO-B levels in the brain, found across different neurological and neurodegenerative disorders including Alzheimer’s disease (AD) and Parkinson’s disease (PD), are associated with deleterious
E. Rodriguez-Vieitez
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Journal of Medicinal Chemistry, 2020
Parkinson's disease (PD) is one of the most common age-related neurodegenerative diseases. Inhibition of monoamine oxidase-B (MAO-B), which is mainly found in the glial cells of the brain, may lead to an elevated level of dopamine (DA) in patients. MAO-B
Chuanfei Jin +4 more
semanticscholar +1 more source
Parkinson's disease (PD) is one of the most common age-related neurodegenerative diseases. Inhibition of monoamine oxidase-B (MAO-B), which is mainly found in the glial cells of the brain, may lead to an elevated level of dopamine (DA) in patients. MAO-B
Chuanfei Jin +4 more
semanticscholar +1 more source