Results 181 to 190 of about 25,878 (248)

Synthesis of 1,2,4-Oxadiazin-5(6H)-One Derivatives and Their Biological Investigation as Monoamine Oxidase Inhibitors. [PDF]

open access: yesMolecules
Presnukhina SI   +13 more
europepmc   +1 more source

Recent advances in Parkinson\u27s disease therapy: use of monoamine oxidase inhibitors.

open access: yes, 2005
Monoamine oxidase inhibitors inhibit dopamine metabolism and are therefore effective in treating Parkinson\u27s disease, a condition associated with progressive striatal dopamine deficiency secondary to degeneration of dopaminergic neurons in the ...
Burgut, F Tuna   +2 more
core  

Enhancing Dopamine Accumulation in Secretory Vesicles of PC12 Cells: Mechanisms, Applications and Limitations

open access: yesJournal of Neurochemistry, Volume 170, Issue 6, June 2026.
Schematic representation of a large dense‐core vesicle in PC12 cells highlighting its main molecular organization. The diagram illustrates the presence of membrane transporters, proton pumps and intravesicular matrix proteins that establish the electrochemical gradients required for neurotransmitter uptake, vesicle acidification and efficient storage ...
Noemi Socas‐Pérez   +2 more
wiley   +1 more source

Design, Synthesis, and Biological Effect Studies of Novel Benzofuran-Thiazolylhydrazone Derivatives as Monoamine Oxidase Inhibitors. [PDF]

open access: yesACS Omega
Osmani Ye D   +9 more
europepmc   +1 more source

Co‐pathologies and biological processes beyond amyloid‐beta and tau in people with Alzheimer's disease: Evidence from clinical cohort studies

open access: yesJournal of Internal Medicine, Volume 299, Issue 6, Page 694-710, June 2026.
Abstract Alzheimer's disease (AD) is neuropathologically defined by amyloid‐beta (Aβ) plaques and tau neurofibrillary tangles. However, co‐pathologies and other pathobiological processes are involved in the pathogenesis of AD, contributing to neurodegeneration and clinical symptoms.
Daniel Ferreira   +9 more
wiley   +1 more source

<i>In Vitro</i> and <i>In Silico</i> ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases. [PDF]

open access: yesACS Chem Neurosci, 2020
Więckowska A   +14 more
europepmc   +1 more source

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