Results 201 to 210 of about 25,878 (248)

Dietary inhibitors of monoamine oxidase A

Journal of Neural Transmission, 2010
Inhibition of monoamine oxidase is one way to treat depression and anxiety. The information now available on the pharmacokinetics of flavonoids and of the components of tobacco prompted an exploration of whether a healthy diet (with or without smoking) provides active compounds in amounts sufficient to partially inhibit monoamine oxidase.
Sarah E, Dixon Clarke, Rona R, Ramsay
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Metabolism of monoamine oxidase inhibitors

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 1989
1. Despite the fact that monoamine oxidase inhibitors have been used clinically and in animal experiments for many years, much still remains unknown about their metabolism. An overview of the metabolic aspects of several monoamine oxidase inhibitors, including phenelzine, tranylcypromine, pheniprazine, pargyline and deprenyl, is presented. 2.
G B, Baker, R T, Coutts
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Pyrogens and Monoamine Oxidase Inhibitors

Nature, 1966
MANY nerve terminals within the hypothalamus contain either noradrenaline or 5-hydroxytryptamine (5-HT) (ref. 1). It has been suggested that these amines may play a part in the thermo-regulatory pathways2–4.
K E, Cooper, W I, Cranston
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Monoamine oxidase inhibitors in hypertension

The American Journal of Cardiology, 1960
Abstract 1. 1. A survey of the literature reveals that the monoamine oxidase inhibitors, 1-isonicotinyl-2-isopropyl hydrazine (iproniazid, Marsilid), betaphenylisopropyl-hydrazine hydrochloride (JB 516, Catron®) and DL-serine-N2-isopropyl hydrazide monohydrochloride (RO4–1038)have antihypertensive effects in man. 2. 2.
M H, MAXWELL, H, BERNSTEIN, S, ROTH, C R, KLEEMAN   +3 more
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Naphthylisopropylamine and N-benzylamphetamine derivatives as monoamine oxidase inhibitors [PDF]

Bioorganic and Medicinal Chemistry, 2009
A series of naphthylisopropylamine and N-benzyl-4-methylthioamphetamine derivatives were evaluated as monoamine oxidase inhibitors. Their potencies were compared with those of a series of amphetamine derivatives, to test if the increase of electron ...
Marcelo Vilches-Herrera, Angelica Fierro, Patricio Iturriaga-Vasquez   +2 more
exaly   +1 more source

New Inhibitor of Monoamine Oxidase

Nature, 1960
THE following is the initial report of a structurally unique monoamine oxidase inhibitor, N-benzyl-N-methyl-2-propynylamine hydrochloride (A19120). This work includes in vitro action of this inhibitor on rat liver mitochondria as well as in vivo inhibition of monoamine oxidase of mouse brain and the liver.
J D, TAYLOR, A A, WYKES, Y C, GLADISH, W B, MARTIN   +3 more
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Metabolism of Monoamine Oxidase Inhibitors

Cellular and Molecular Neurobiology, 1999
1. The principal routes of metabolism of the following monoamine oxidase inhibitors (MAOIs) are described: phenelzine, tranylcypromine, pargyline, deprenyl, moclobemide, and brofaromine. 2. Acetylation of phenelzine appears to be a minor metabolic pathway.
G B, Baker, L J, Urichuk, K F, McKenna, S H, Kennedy   +3 more
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Monoamine oxidase inhibitor overdose

Annals of Emergency Medicine, 1984
Described is the clinical course of a 26-year-old woman who died following an overdose of the MAO inhibitor phenelzine. Signs and symptoms of toxicity were delayed in onset. Initial findings of excessive neuromuscular activity were followed by severe hyperthermia, coma, cardiovascular collapse, acute renal failure, hemolysis, rhabdomyolysis, and ...
C H, Linden, B H, Rumack, C, Strehlke
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Inhibitor Design for Monoamine Oxidases

Current Pharmaceutical Design, 2013
Flavin-containing monoamine oxidases (MAO A and MAO B) located on the outer membrane of mitochondria oxidise amines and generate hydrogen peroxide. Inhibitors alleviate depression by increasing neurotransmitter levels in the brain. Elevation of neurotransmitters,although an established outcome, is a delicate balance because complete lack of MAO A is ...
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Another look at the monoamine oxidases and the monoamine oxidase inhibitor drugs

Life Sciences, 1974
Publisher Summary This chapter discusses the monoamine oxidases (MAO) and the MAO inhibitor drugs. Phenylethylamines and indolethylamines appear to be the endogenous substrates for tissue MAO. The m-O-methylated catecholamine metabolites have lower values than the parent amines.
N H, Neff, H Y, Yang
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