Results 121 to 130 of about 35,566 (181)

Role of monoamine oxidases to oxidative modification of myocardial proteins in rats with alloxan diabetes

Сибирский научный медицинский журнал
Diabetes mellitus is associated with a high risk of developing coronary heart disease, cardiac autonomic neuropathy, and diabetic cardiomyopathy, all of which involve oxidative stress mediated by insulin deficiency. The contribution of monoamine oxidases
V. S. Noskova, P. K. Vinel, E. F. Agletdinov, Yu. M. Shatrova, A. I. Sinitskii   +4 more
doaj   +1 more source

Patients With Atypical Symptoms of Depression Respond Better to Lithium Augmentation Than Patients Without Atypical Symptoms

Acta Psychiatrica Scandinavica, Volume 154, Issue 5, Page 376-383, November 2026.
ABSTRACT Introduction Understanding the differences in treatment response between subtypes of major depressive disorder (MDD) may help to prevent lengthy trial‐and‐error processes by identifying effective treatment options. The aim of the study was to investigate the impact of atypical features of MDD (MDD‐A) on the response to lithium augmentation (LA)
Hannah Buchbauer, Mazda Adli, Peter Schlattmann, Maximilian Berger, Tom Bschor, Thomas Stamm, Joachim Behr, Roland Ricken, Pichit Buspavanich   +8 more
wiley   +1 more source

Monoamine Oxidases Desensitize Intracellular β₁AR Signaling in Heart Failure. [PDF]

Circ Res, 2021
Wang Y, Zhao M, Shi Q, Xu B, Zhu C, Li M, Mir V, Bers DM, Xiang YK.   +8 more
europepmc   +1 more source

Perivascular Spaces as Determinants of Amyloid, Tau, and Vascular Biomarker Progression

Annals of Neurology, Volume 100, Issue 4, Page 695-708, October 2026.
Objective Magnetic resonance imaging (MRI)‐visible enlarged perivascular spaces (PVS) are markers of cerebral small vessel disease (SVD) and aging, processes implicated in both neurodegenerative and cerebrovascular pathologies. However, longitudinal positron emission tomography (PET) studies examining PVS as a mechanism underlying Alzheimer's disease ...
Audrey Low, Jeffrey L. Gunter, Mingzhao Hu, Sheelakumari Raghavan, Scott A. Przybelski, Christopher G. Schwarz, Kejal Kantarci, Val J. Lowe, Ronald C. Petersen, Jonathan Graff‐Radford, Clifford R. Jack Jr, Prashanthi Vemuri   +11 more
wiley   +1 more source

Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella, Khai‐Lin Hew, Yeun‐Mun Choo   +2 more
wiley   +1 more source

Exploring the Neuropharmacological Potential of Ligustrum sinense Relevant to Parkinson's Disease: In Vivo and In Silico Study

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Ligustrum sinense (L. sinense) leaf extract exhibited moderate antioxidant activity (DPPH IC50 = 73.56 ± 2.18 µg/mL) and was evaluated for neuropharmacological effects at 200 and 400 mg/kg using elevated plus maze, open‐field, hole‐cross, and hole‐board tests.
Sowmitro Das, S. M. Istiaque Hamim, Md Nazmul Hasan Zilani, Kazi Sneha Chhando, Puza Das, Md Ridoy Hossain, Md. Imtiaz, Jebin Tasmin, Roney Miah, Md. Nazmul Hasan   +9 more
wiley   +1 more source

The discrediting of the monoamine hypothesis

, 2012
Marty Hinz1, Alvin Stein2, Thomas Uncini31Clinical Research, NeuroResearch Clinics, Inc, Cape Coral, FL, 2Stein Orthopedic Associates, Plantation, FL, 3Fairview University Medical Center, Hibbing, MN, USABackground: The monoamine hypothesis has been ...
Uncini T, Stein A, Hinz M
core  

An efficient method to access spiro pseudoindoxyl ketones: evaluation of indoxyl and their N-benzylated derivatives for inhibition of the activity of monoamine oxidases. [PDF]

RSC Adv, 2023
Perumal K, Lee J, Annes SB, Ramesh S, Rangarajan TM, Mathew B, Kim H.   +6 more
europepmc   +1 more source

Effects of Trimethoprim on Three Previously Proposed Putative Biomarkers for OCT2/MATE‐Mediated Renal Drug‐Drug Interactions in Healthy Volunteers

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1016-1026, October 2026.
Regulatory agencies request the assessment of the potential of new drugs to cause transporter‐mediated drug‐drug interactions (DDI). This assessment can be improved by integrating endogenous biomarkers during drug development. Regarding the renal excretion of drugs such as metformin, the organic cation transporter (OCT) 2 and multidrug and toxin ...
Jana Picurová, Fabian Müller, Daniel Auge, Jörg König, Martin F. Fromm, Arne Gessner   +5 more
wiley   +1 more source

Design, Synthesis, and Biological Activities of Pyrrolylethanoneamine Derivatives, a Novel Class of Monoamine Oxidases Inhibitors

, 2016
Pyrrolylethanoneamines 1−12, 18−23 and related amino alcohols 13−15, 24−27 were synthesized and tested against monoamine oxidases A and B (MAO-A and MAO-B) enzymes.
Bruno Gallinella (2268037), Olivia Befani (2501338), Paola Turini (2501341), Alessandra Roux (1265001), Rosella Ferretti (1705726), Marino Artico (2093173), Tiziana Meninno (2678590), Roberto Cirilli (1456552), Roberto Di Santo (805171), Paola Palmegiani (2678587), Francesco La Torre (2377144), Roberta Costi (808376), Enzo Agostinelli (660855)   +12 more
core   +1 more source