Results 131 to 140 of about 35,566 (181)

Characterisation of the flavin adenine dinucleotide binding region in Myxococcus xanthus protoporphyrinogen oxidase [PDF]

, 2011
This dissertation focuses on protoporphyrinogen oxidase (PPOX), the penultimate enzyme in the haem biosynthetic pathway. Partial defects in PPOX result in variegate porphyria, an autosomal dominant disorder.
Boateng, Mavis O
core   +1 more source

A Multi‐Scale Computational Framework for Anti‐Persister Tuberculosis Drug Discovery

Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
This review presents an integrated QSAR–scaffold design–docking–MD framework for discovering anti‐persister tuberculosis agents active in dormant granuloma‐like conditions. By targeting Mtb bioenergetics and prioritising dual NDH‐2/cytochrome bd oxidase inhibition, the workflow advances rational design of candidates with higher resistance barriers ...
Said Moshawih, Anguraj Moulishankar, Chee Yan Choo, Khang Wen Goh, Chrismawan Ardianto, Azam Che Idris, Long Chiau Ming   +6 more
wiley   +1 more source

Inhibition of Human Monoamine Oxidases A and B by Specialized Metabolites Present in Fresh Common Fruits and Vegetables. [PDF]

Plants (Basel), 2022
Marzo CM, Gambini S, Poletti S, Munari F, Assfalg M, Guzzo F.   +5 more
europepmc   +1 more source

Coumarin-Based Dual Inhibitors of Human Carbonic Anhydrases and Monoamine Oxidases Featuring Amino Acyl and (Pseudo)-Dipeptidyl Appendages: In Vitro and Computational Studies. [PDF]

Molecules, 2022
Agamennone M, Fantacuzzi M, Carradori S, Petzer A, Petzer JP, Angeli A, Supuran CT, Luisi G.   +7 more
europepmc   +1 more source

Molecular Modeling and Experimental Evaluation of Non-Chiral Components of Bergamot Essential Oil with Inhibitory Activity against Human Monoamine Oxidases. [PDF]

Molecules, 2022
Catalano R, Procopio F, Chavarria D, Benfeito S, Alcaro S, Borges F, Ortuso F.   +6 more
europepmc   +1 more source

Novel targets for “old” polyamine analogues: monoamine oxidases and benextramine derivatives

, 2018
Benextramine is a well kown tetraamine disulfide acting as irreversible α-adrenergic antagonist and able to hit additional targets involved in neurodegeneration, such as nicotinic and muscarinic receptors and acetylcholinesterase enzyme.
Giorgio Cozza, Michela Rosini, Maria Luisa Di Paolo, Francesca Zonta, Stefania Sarno, Elirosa Minniti, Anna Minarini, Andrea Milelli   +7 more
core   +1 more source

Targeting monoamine oxidases for the treatment of betel quid dependence: a potential pharmacological and neurobiological approach. [PDF]

Front Pharmacol
Chakraborty S, Choudhury AH, Sharma I, Choudhury Y.   +3 more
europepmc   +1 more source

Targeting monoamine oxidases in cancer: advances and opportunities. [PDF]

Trends Mol Med
Wei J, Wu BJ.
europepmc   +1 more source

Cardiac monoamine oxidases: at the heart of mitochondrial dysfunction. [PDF]

Cell Death Dis, 2020
Mialet-Perez J, Parini A.
europepmc   +1 more source

Monoamine oxidases are mediators of oxidative stress in human varicose Veins: interactions with obesity, inflammation, and angiotensin II. [PDF]

Mol Cell Biochem
Raţiu S, Sturza A, Muntean PS, Borza C, Bratu T, Muntean DM.   +5 more
europepmc   +1 more source