Results 101 to 110 of about 4,684 (142)

The ketogenic diet alters microbiome-metabolome profiles to improve West syndrome therapy. [PDF]

Pediatr Investig
Xie G, Zhou Q, Liao J, Zheng Y, Wang W, Shen K.   +5 more
europepmc   +1 more source

The Role of Solute Carrier Family Transporters in Hepatic Steatosis and Hepatic Fibrosis. [PDF]

J Clin Transl Hepatol
Zhang C, Yang X, Xue Y, Li H, Zeng C, Chen M.   +5 more
europepmc   +1 more source

Comprehensive In Silico Investigation of L-Glutamine Transporters and Metabolism in Glioblastoma. [PDF]

Pharmaceuticals (Basel)
Kumar S, Wang CY, Lalwani HK, Ngadio JL, Wulandari FS, Solomon DD, Liu HP.   +6 more
europepmc   +1 more source

Uptake of Aristolochic Acid I into Caco-2 Cells by Monocarboxylic Acid Transporters

Biological and Pharmaceutical Bulletin, 2014
The uptake mechanism of aristolochic acid I (AAI) was investigated using Caco-2 cells cultured on dishes and permeable membranes. The uptake of AAI from the apical membrane of Caco-2 cells cultured on a dish was rapid, and a decrease in the pH of the incubation medium significantly increased uptake.
Chiho Ohta, Koichi Haragutchi, Tetsuya Endo   +2 more
exaly   +4 more sources

Transepithelial Transport of Ferulic Acid by Monocarboxylic Acid Transporter in Caco-2 Cell Monolayers

Bioscience, Biotechnology and Biochemistry, 2003
Our previous study (Biosci. Biotechnol. Biochem., 66, 2449-2457 (2002)), suggested that ferulic acid was transported via a monocarboxylic acid transporter (MCT). Transepithelial transport of ferulic acid was examined in this study by directly measuring the rate of its transport across Caco-2 cell monolayers.
Yutaka Konishi
exaly   +3 more sources

Uptake of phenoxyacetic acid derivatives into Caco-2 cells by the monocarboxylic acid transporters

Toxicology Letters, 2009
The uptake mechanism of phenoxyacetic acid (PA) and its chlorine derivatives, 4-chlorophenoxyacetic acid (4-CPA), 2,4-dichlorophenoxyacetic acid (2,4-D), and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), was investigated using Caco-2 cells. The cells were incubated with PA, 4-CPA, 2,4-D or 2,4,5-T at pH 6.0 and 37 degrees C.
Tetsuya Endo
exaly   +3 more sources

Expression of monocarboxylic acid transporters (MCT) in brain cells

Neurochemistry International, 2003
Katarzyna Nalecz
exaly   +2 more sources

Monocarboxylic acid transporters, MCT1 and MCT2, in cortical astrocytes in vitro and in vivo

American Journal of Physiology - Cell Physiology, 2000
We used sequence-specific antibodies to characterize two monocarboxylic acid transporters, MCT1 and MCT2, in astrocytes. Both proteins are expressed in primary cultures of cortical astrocytes, as indicated by immunoblotting and immunofluorescence. Both MCT1 and MCT2 are present in small, punctate structures in the cytoplasm and at the cell membrane ...
Robert Bloch, Mary C Mckenna, Wendy G Resneck   +2 more
exaly   +3 more sources

The role of monocarboxylate transporters in uptake of lactic acid in HeLa cells

International Journal of Pharmaceutics, 2006
This study was aimed to identify the monocarboxylate transporters (MCTs) in HeLa cells and to delineate their role in transportation of L-lactic acid. The functional role of MCTs in lactic acid transport was evaluated at various mucosal pHs (4.5-7.4) or in the presence of various loading doses (0.2-2mM) of lactic acid, MCT substrates (nicotinic acid, n-
Sravanthi, Cheeti, Bharat K, Warrier, Chi H, Lee   +2 more
openaire   +2 more sources

Participation of a Proton-Cotransporter, MCT1, in the Intestinal Transport of Monocarboxylic Acids

Biochemical and Biophysical Research Communications, 1995
A molecular mechanism for the intestinal monocarboxylic acid transport was characterized by using a proton/monocarboxylate transporter, MCT1, in Chinese hamster ovary (CHO) cells, first found by Garcia et al. (Cell, 76, 865-873, 1994). Northern blotting analysis showed that MCT1-isomers exist in the rat and rabbit intestinal enterocytes and Caco-2 ...
I, Tamai, H, Takanaga, H, Maeda, Y, Sai, T, Ogihara, H, Higashida, A, Tsuji   +6 more
openaire   +2 more sources