Results 1 to 10 of about 1,828,522 (388)

High-throughput bactericidal assays for monoclonal antibody screening against antimicrobial resistant Neisseria gonorrhoeae

open access: yesFrontiers in Microbiology, 2023
Neisseria gonorrhoeae (gonococcus) is an obligate human pathogen and the etiological agent of the sexually transmitted disease gonorrhea. The rapid rise in gonococcal resistance to all currently available antimicrobials has become a significant public ...
Samuele Stazzoni   +7 more
doaj   +1 more source

GPI-Anchored Fibromodulin as a Novel Target in Chronic Lymphocytic Leukemia: Diagnostic and Therapeutic Implications [PDF]

open access: yesIranian Journal of Immunology, 2019
Background: We have previously reported the aberrant expression of Fibromodulin (FMOD) in patients with chronic lymphocytic leukemia (CLL). Although FMOD has been considered as a cytoplasmic or secretory protein, we discovered the cell surface expression
Lia Farahi   +8 more
doaj   +1 more source

A new dawn for monoclonal antibodies against antimicrobial resistant bacteria

open access: yesFrontiers in Microbiology, 2022
Antimicrobial resistance (AMR) is a quickly advancing threat for human health worldwide and almost 5 million deaths are already attributable to this phenomenon every year.
Marco Troisi   +6 more
doaj   +1 more source

Anatomy of Omicron BA.1 and BA.2 neutralizing antibodies in COVID-19 mRNA vaccinees

open access: yesNature Communications, 2022
Here, Andreano and Paciello et al. show, at single cell level, the functional and genetic characteristics underlying the Omicron BA.1 and BA.2 cross-protective antibody response in naïve and previously infected COVID-19 vaccinees.
Emanuele Andreano   +18 more
doaj   +1 more source

Giant cell arteritis

open access: yesLiječnički vjesnik, 2021
Giant cell arteritis (GCA) is the most common vasculitis of older age. It usually affects the branches of carotid arteries, especially temporal and ophthalmic artery.
Dijana Perković   +6 more
doaj   +1 more source

Determining reference ranges for immunological cells of healthy indigenous individuals from a region in Brazil [PDF]

open access: yesEinstein (São Paulo), 2023
Objective The establishment of reference values for a subset of leukocytes is common in clinical practice, and ethnic variations are strongly associated with disease development.
Isa Rita Brito de Morais   +14 more
doaj   +1 more source

Therapeutic options for the treatment of interstitial lung diseases in systemic rheumatic diseases – systemic sclerosis as an example [PDF]

open access: yesLiječnički vjesnik, 2022
Systemic sclerosis is a multisystem autoimmune disorder characterized by widespread fibrosis, primarily of the skin but also of the lung parenchyma. Interstitial lung disease is one of the most severe manifestations of the disease and a leading cause of ...
Marko Barešić, Branimir Anić
doaj   +1 more source

The monoclonal myth [PDF]

open access: yesBioengineered Bugs, 2010
Most researchers confidently assume that transformation of recombinant plasmid libraries into microbial hosts followed by outgrowth of isolated colonies results in a "one cell-one mutant gene-one protein variant" paradigm. Indeed, this assumption is supported by the overwhelming majority of published studies employing bacterial expression hosts.
Thomas C. Scanlon   +3 more
openaire   +2 more sources

mRNA vaccines and hybrid immunity use different B cell germlines against Omicron BA.4 and BA.5

open access: yesNature Communications, 2023
Omicron strains of SARS-CoV-2 have displayed high transmissibility and immunological escape to antibody responses derived from natural infection and vaccination.
Emanuele Andreano   +15 more
doaj   +1 more source

Development of a triple antibody sandwich enzyme-linked immunosorbent assay for cassava mosaic disease detection using a monoclonal antibody to Sri Lankan cassava mosaic virus

open access: yesVirology Journal, 2021
Background Cassava mosaic disease (CMD) is one of the most devastating viral diseases for cassava production in Africa and Asia. Accurate yet affordable diagnostics are one of the fundamental tools supporting successful CMD management, especially in ...
Saengsoon Charoenvilaisiri   +9 more
doaj   +1 more source

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