Therapeutic options for the treatment of interstitial lung diseases in systemic rheumatic diseases – systemic sclerosis as an example [PDF]
Liječnički vjesnik, 2022 Systemic sclerosis is a multisystem autoimmune disorder characterized by widespread fibrosis, primarily of the skin but also of the lung parenchyma. Interstitial lung disease is one of the most severe manifestations of the disease and a leading cause of ...
Marko Barešić, Branimir Anić
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Frontiers in Microbiology, 2023 Neisseria gonorrhoeae (gonococcus) is an obligate human pathogen and the etiological agent of the sexually transmitted disease gonorrhea. The rapid rise in gonococcal resistance to all currently available antimicrobials has become a significant public ...
Samuele Stazzoni +7 more
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GPI-Anchored Fibromodulin as a Novel Target in Chronic Lymphocytic Leukemia: Diagnostic and Therapeutic Implications [PDF]
Iranian Journal of Immunology, 2019 Background: We have previously reported the aberrant expression of Fibromodulin (FMOD) in patients with chronic lymphocytic leukemia (CLL). Although FMOD has been considered as a cytoplasmic or secretory protein, we discovered the cell surface expression
Lia Farahi +8 more
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A new dawn for monoclonal antibodies against antimicrobial resistant bacteria
Frontiers in Microbiology, 2022 Antimicrobial resistance (AMR) is a quickly advancing threat for human health worldwide and almost 5 million deaths are already attributable to this phenomenon every year.
Marco Troisi +6 more
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Anatomy of Omicron BA.1 and BA.2 neutralizing antibodies in COVID-19 mRNA vaccinees
Nature Communications, 2022 Here, Andreano and Paciello et al. show, at single cell level, the functional and genetic characteristics underlying the Omicron BA.1 and BA.2 cross-protective antibody response in naïve and previously infected COVID-19 vaccinees.
Emanuele Andreano +18 more
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A Case of Light Chain Deposition Disease Leading to Acute Liver Failure and Review of Literature
Diseases, 2023 Light chain deposition disease (LCDD) is a monoclonal immunoglobulin deposition disease characterized by light chain deposition in soft tissues and viscera, causing systemic organ dysfunction with an underlying lymphoproliferative disorder.
Mustafa Gandhi +7 more
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Immunogenicity Risk Assessment of Spontaneously Occurring Therapeutic Monoclonal Antibody Aggregates
Frontiers in Immunology, 2022 Aggregates of therapeutic proteins have been associated with increased immunogenicity in pre-clinical models as well as in human patients. Recent studies to understand aggregates and their immunogenicity risks use artificial stress methods to induce high
Michael D. Swanson +4 more
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Determining reference ranges for immunological cells of healthy indigenous individuals from a region in Brazil [PDF]
Einstein (São Paulo), 2023 Objective The establishment of reference values for a subset of leukocytes is common in clinical practice, and ethnic variations are strongly associated with disease development.
Isa Rita Brito de Morais +14 more
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mRNA vaccines and hybrid immunity use different B cell germlines against Omicron BA.4 and BA.5
Nature Communications, 2023 Omicron strains of SARS-CoV-2 have displayed high transmissibility and immunological escape to antibody responses derived from natural infection and vaccination.
Emanuele Andreano +15 more
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Virology Journal, 2021 Background Cassava mosaic disease (CMD) is one of the most devastating viral diseases for cassava production in Africa and Asia. Accurate yet affordable diagnostics are one of the fundamental tools supporting successful CMD management, especially in ...
Saengsoon Charoenvilaisiri +9 more
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