Results 111 to 120 of about 771,983 (316)

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

Advanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song, Valentin A. Milichko, Ziqiao Ding, Wen Li, Bei Kang, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Novel Type of Monoclonal Antibodies against Cyclic GMP and Application to Immunocytochemistry of the Rat Brain

, 1988
Motoyoshi Sakaue, Takayoshi Kuno, Chikako Tanaka   +2 more
openalex   +1 more source

Enhancement of growth hormone activity in vivo by monoclonal antibodies: potential for autoimmunization [PDF]

, 1988
R. Aston, A. T. Holder, Michael Wallis, P. C. Bates, R. Bomford   +4 more
openalex   +1 more source

Machine Learning Guided Design of Nerve‐On‐A‐Chip Platforms with Promoted Neurite Outgrowth

Advanced Functional Materials, EarlyView.
Compared to labor‐intensive trial‐and‐error experimentation, a machine learning (ML)‐guided workflow, incorporating cell viability assays, data augmentation, ensemble modeling, and model interpretation, is developed to accelerate nerve‐on‐a‐chip optimization and uncover data‐driven design principles.
Tsai‐Chun Chung, Chu‐Chun Liang, Min‐Wei Huang, Tianle Chen, Joshua M. Little, Snehi Shrestha, Yi‐Chen Ethan Li, I‐Chi Lee, Po‐Yen Chen   +8 more
wiley   +1 more source

Evaluating T-Cell Immunoglobulin Mucin-3 (TIM-3) Receptor in the Growth Inhibition of Acute Lymphoblastic Leukemia (ALL) Cell Lines

مجله دانشکده پزشکی اصفهان, 2015
Background: T-cell immunoglobulin-mucin (TIM) is a cell-surface and transmembrane glycoprotein. TIM-3 plays a pivotal role in proliferation, invasion and metastasis of tumor cells.
Narges Zargar-Balajam, Mahdi Shabani, Mansoreh Haghighi, Ahmad Ali Bayat, Mahmoud Aghaei   +4 more
doaj  

Antigenic Characterization of Measles and SSPE Virus Haemagglutinin by Monoclonal Antibodies

, 1981
Volker ter Meulen, S. Löffler, M. J. Carter, J. R. Stephenson   +3 more
openalex   +1 more source

Site-specific inhibition of myosin-mediated motility in vitro by monoclonal antibodies. [PDF]

, 1985
Paula Flicker, Gary Peltz, Michael P. Sheetz, P Parham, James A. Spudich   +4 more
openalex   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

Advanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao, Tong Ye, Mingjiang Liu, Jingchao Gao, Lian Tan, Qian Dong, Qingbo Lv, Qianqian Ye, Yu Wang   +8 more
wiley   +1 more source

T CELL DEPLETION OF HUMAN BONE MARROW USING MONOCLONAL ANTIBODY AND COMPLEMENT-MEDIATED LYSIS

, 1983
Thomas G. Sharp, David H. Sachs, Anthony S. Fauci, Gerald L. Messerschmidt, Steven A. Rosenberg   +4 more
openalex   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source