Results 131 to 140 of about 801,490 (249)

Multiscale Hybrid Surface Topographies Orchestrate Immune Regulation, Antibacterial Defense, and Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash, Jacob Robins, J. Scott VanEpps, Minji Kim, Jouha Min   +4 more
wiley   +1 more source

Technologies for Monoclonal Antibody Discovery and Development. [PDF]

Int J Mol Sci
Han KH, Li YC, Parveen R, Venkataraman S, Lin CW.   +4 more
europepmc   +1 more source

The Development of Methods to Account for Physiologic Dynamic Changes and Their Effects on the Pharmacokinetics of Therapeutic Monoclonal Antibodies and other Therapeutics

, 2017
Josiah Ryman, Josiah Ryman
openalex   +1 more source

A Novel Microfluidic System for 3D Epidermis and Full‐Thickness Skin Growth for Nanoparticle Safety Assessment

Advanced Healthcare Materials, EarlyView.
This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa, Ana B. Carneiro, Filipa Lebre, João Meneses, Alar Ainla, Cacilda Moura, Ernesto Alfaro‐Moreno, Ana R. Ribeiro   +7 more
wiley   +1 more source

Self-Driving Development of Perfusion Processes for Monoclonal Antibody Production. [PDF]

Biotechnol Bioeng
Gadiyar CJ, Müller C, Vuillemin T, Bielser JM, Souquet J, Fagnani A, Sokolov M, von Stosch M, Feidl F, Butté A, Cruz Bournazou MN.   +10 more
europepmc   +1 more source

REGN1908‐1909 monoclonal antibodies block Fel d 1 in cat allergic subjects: Translational pharmacokinetics and pharmacodynamics

, 2021
Mohamed Kamal, Robert Dingman, Claire Q. Wang, Ching‐Ha Lai, Manoj Rajadhyaksha, Michelle DeVeaux, Jamie Orengo, Allen Radin, John D. Davis   +8 more
openalex   +1 more source

Precise Control of Drug Release in Machine Learning‐Designed Antibody‐Eluting Implants for Postoperative Scarring Inhibition in Glaucoma

Advanced Healthcare Materials, EarlyView.
We developed a micro‐sized, biocompatible implant for postoperative sustained delivery of anti‐fibrotic antibodies in glaucoma surgery. Machine learning‐guided optimization of polymer composition, implant geometry, and porosity enabled precise control of drug release.
Mengqi Qin, Wenbing Jiang, Kai Xin Thong, Zeynep Ulker, Brihitejas Patel, Cynthia Yu‐Wai‐Man   +5 more
wiley   +1 more source

Preclinical characterisation of the protective capacity of an anti-nucleoprotein hRSV monoclonal antibody. [PDF]

EBioMedicine
Farías MA, Andrade CA, Loaiza RA, Rodríguez-Guilarte L, Muñoz JT, Pereira-Sánchez P, Muñoz-Durango N, Pizarro-Ortega MS, Diethelm-Varela B, Pereira-Serrano A, Ramírez RA, Chávez JL, Bohmwald K, Soto JA, González PA, Bueno SM, Kalergis AM.   +16 more
europepmc   +1 more source

Programmed death-ligand 1 (PD-L1)-targeted monoclonal antibodies

, 2019
Yuranga Weerakkody, Daniel Bell, Ayla Al Kabbani   +2 more
openalex   +1 more source

Monoclonal antibodies raised against 167–180 aa sequence of human carbonic anhydrase XII inhibit its enzymatic activity [PDF]

, 2014
Dovile Dekaminaviciute, Visvaldas Kairys, Milda Zilnyte, Vilma Petrikaitė, Vaida Jogaitė, Jurgita Matulienė, Živilė Gudlevičienė, Daniela Vullo, Claudiu T. Supuran, Aurelija Žvirblienė   +9 more
openalex   +1 more source