Results 141 to 150 of about 759,957 (341)

Terahertz Metamaterial Sensors: Design Theory, Optimization Approach, and Advancements in Biosensing Applications

open access: yesAdvanced Materials Technologies, EarlyView.
This review provides an in‐depth overview of the design principles and optimization strategies for terahertz (THz) metamaterials (MMs) sensors based on the dielectric perturbation theory. Various structures and methods are explored to enhance sensor performance, focusing on improving sensitivity and Q‐factor.
Lei Cao   +9 more
wiley   +1 more source

Uncertainty Quantification of Antibody Measurements: Physical Principles and Implications for Standardization [PDF]

open access: yesarXiv
Harmonizing serology measurements is critical for identifying reference materials that permit standardization and comparison of results across different diagnostic platforms. However, the theoretical foundations of such tasks have yet to be fully explored in the context of antibody thermodynamics and uncertainty quantification (UQ). This has restricted
arxiv  

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

open access: yesAdvanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin   +8 more
wiley   +1 more source

T10B9 monoclonal antibody: A short-acting nonstimulating monoclonal antibody that spares γδ T-cells and treats and prevents cellular rejection

open access: yesDrug Design, Development and Therapy, 2009
Thomas H Waid1, John S Thompson1, Maria Siemionow2, Stephen A Brown1 1Department of Internal Medicine, University of Kentucky, Lexington, Kentucky, USA; 2Cleveland Clinic, Cleveland, Ohio, USAAbstract: T10B9.1A-31/MEDI-500 is a ...
Thomas H Waid   +3 more
doaj  

Electrostatics and viscosity are strongly linked in concentrated antibody solutions [PDF]

open access: yesarXiv
Monoclonal antibodies are among the most promising therapeutic agents in modern medicine, yet their formulation into high-concentration solutions for subcutaneous self-administration poses a major challenge. A key obstacle is the marked increase in viscosity often observed under these conditions.
arxiv  

Picomolar Detection of Tau Protein Using 1D Photonic Crystal Biochips for Alzheimer's Disease Diagnosis

open access: yesAdvanced Sensor Research, EarlyView.
Elevated levels of Tau in cerebrospinal fluids or other body fluids are associated with the progression of Alzheimer's disease. An optical technique, based on a dual label‐free and fluorescence operation mode, is developed to detect Tau protein in both standard running buffer and cerebrospinal fluid.
Alberto Sinibaldi   +7 more
wiley   +1 more source

Biochemical characterization of human melanoma cell surfaces: dissection with monoclonal antibodies.

open access: green, 1980
Kenneth F. Mitchell   +3 more
openalex   +1 more source

Autologous Peripheral Vγ9Vδ2 T Cell Synergizes with αβ T Cell Through Antigen Presentation and BTN3A1 Blockade in Immunotherapy of Cervical Cancer

open access: yesAdvanced Science, EarlyView.
This study provides proof‐of‐concept evidence showing that through direct killing, antigen presentation, and competitively binding to BTN3A1, Vγ9Vδ2 T cells amplified from cervical cancer (CC) patients can synergize with αβ T cells to exert anti‐CC function both in vitro and in vivo.
Min Wu   +21 more
wiley   +1 more source

Sustained Vaccine Exposure Elicits More Rapid, Consistent, and Broad Humoral Immune Responses to Multivalent Influenza Vaccines

open access: yesAdvanced Science, EarlyView.
This work presents an injectable polymer‐nanoparticle hydrogel depot platform for delivering multivalent influenza vaccines which induces stronger and more durable immune responses. The technology provides broader protection, including against heterologous and potential pandemic strains (H5N1, H7N9, H9N2), and enhances the effectiveness of commercial ...
Olivia M. Saouaf   +7 more
wiley   +1 more source

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