Results 191 to 200 of about 801,490 (249)

A phase 1 experimental medicine study of anti-CD3 monoclonal antibody in rheumatoid arthritis. [PDF]

Immunother Adv
Lawson CA, Harry R, Griffiths B, Hale G, Waldmann H, Isaacs JD.   +5 more
europepmc   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Robust and Reproducible Monoclonal Antibody Production Using a Transgenic Silkworm System. [PDF]

Int J Mol Sci
Yageta S, Nagata Y, Shimizu M, Yasaka N, Iwasa T, Nakajima T, Kuwata T, Matsushita S, Tomita M.   +8 more
europepmc   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Therapeutic Potential of an Anti-CD44v6 Monoclonal Antibody in Xenograft Models of Colorectal and Gastric Cancer. [PDF]

Cells
Hirayama A, Tanaka T, Ohishi T, Shinoda K, Nakamura T, Nomura A, Kojo N, Araki H, Suzuki K, Kaneko MK, Suzuki H, Kato Y.   +11 more
europepmc   +1 more source

Monoclonal Antibodies to Polioviruses

, 1983
Albert D. M. E. Osterhaus, Anton L. vanWezel, Ton G. Hazendonk, F. G. C. M. UytdeHaag, J. A. A. M. van Asten, Bert van Steen iacute s   +5 more
openalex   +2 more sources

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

Advanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery, Lauriane Gérémie, Julie Brun, Lucas Chassatte, Giacomo Gropplero, Réda Bouras, Jieun Choo, Bertrand Cinquin, Alba Marcellan, Danijela Matic Vignjevic, Stéphanie Descroix   +10 more
wiley   +1 more source

A Soft Microrobot for Single‐Cell Transport, Spheroid Assembly, and Dual‐Mode Drug Screening

Advanced Materials, EarlyView.
A soft, untethered hydrogel microrobot enables precise single‐cell delivery, self‐assembly into 3D spheroids, and real‐time thermal actuation. Driven by light‐induced convection and embedded with gold nanorods and temperature sensors, the microrobot guides cells, modulates local microenvironments, and supports drug testing.
Philipp Harder, Nergishan İyisan, Yukun Wang, Berna Özkale   +3 more
wiley   +1 more source

Interdomain Interactions Modulate Refolding Kinetics and Aggregation in a Monoclonal Antibody. [PDF]

J Am Soc Mass Spectrom
Trolese P, Pierangelini A, Fongaro B, Polverino de Laureto P.   +3 more
europepmc   +1 more source

Clinical and immunological outcomes of SARS-CoV-2-infected vaccine responders, vaccine non-responders, and unvaccinated patients evaluated for neutralizing monoclonal antibody treatment at a single German tertiary care center: a retrospective cohort study with prospective follow-up [PDF]

Julian Triebelhorn, Jochen Schneider, Christoph D. Spinner, Roman Iakoubov, Florian Voit, Laura Wagner, Johanna Erber, Kathrin Rothe, Achim Berthele, Verena Pernpeintner, Elias Strauss, Lutz Renders, Anja Willmann, M. Minić, Emanuel Vogel, Catharina Christa, Dieter Hoffmann, Ulrike Protzer, Samuel Jeske   +18 more
openalex   +1 more source