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Image_2_CD20+ T cells in monoclonal B cell lymphocytosis and chronic lymphocytic leukemia: frequency, phenotype and association with disease progression.pdf [PDF]
IntroductionIn monoclonal B cell lymphocytosis (MBL) and chronic lymphocytic leukemia (CLL), the expansion of malignant B cells disrupts the normal homeostasis and interactions between B cells and T cells, leading to immune dysregulation.
Sandra Silva (3520043) +35 more
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Case Reports in Oncological Medicine, 2016 The cooccurrence of more than one oncologic illness in a patient can present a diagnostic challenge. Here we report an unusual case of concomitant existence of multiple myeloma, breast cancer, and monoclonal B-cell lymphocytosis on initial presentation ...
A. Vennepureddy +4 more
doaj +1 more source
Haematologica, 2014 In chronic lymphocytic leukemia, usually a monoclonal disease, multiple productive immunoglobulin heavy chain gene rearrangements are identified sporadically. Prognostication of such cases based on immunoglobulin heavy variable gene mutational status can
Karla Plevova +9 more
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Case Reports in HematologyThis case describes an exceptionally rare co-occurrence of Hodgkin lymphoma (HL) and T-cell large granular lymphocytic leukaemia (T-LGLL), highlighting the diagnostic and therapeutic complexity of dual lymphoid neoplasms.
Daniel van Tonder +2 more
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Image_1_CD20+ T cells in monoclonal B cell lymphocytosis and chronic lymphocytic leukemia: frequency, phenotype and association with disease progression.pdf [PDF]
IntroductionIn monoclonal B cell lymphocytosis (MBL) and chronic lymphocytic leukemia (CLL), the expansion of malignant B cells disrupts the normal homeostasis and interactions between B cells and T cells, leading to immune dysregulation.
Sandra Silva (3520043) +35 more
core +1 more source
Telomere length analysis in monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia Binet A
Brazilian Journal of Medical and Biological ResearchMonoclonal B-cell lymphocytosis (MBL) is an asymptomatic clinical entity characterized by the proliferation of monoclonal B cells not meeting the diagnosis criteria for chronic lymphocytic leukemia (CLL).
F.M. Furtado +7 more
doaj +1 more source
Leukemia Research Reports, 2015 Chronic lymphocytic leukemia (CLL) is the most frequent leukemia in Western adults. It was suggested that transcripts from a reciprocal trans-splicing event between YPEL5 and PPP1CB were present exclusively in CLL patients (more than 90%).
Karl Vandepoele +2 more
doaj +1 more source
Clonal Expansion of B and T lymphocytes Defines a Spectrum of Monoclonal Lymphocytosis [PDF]
, 2011 Monoclonal B lymphocytosis (MBL) has been recognized as a novel diagnostic condition. This study aims at the identification of clonal lymphocytosis in the patients with asymptomatic lymphocytosis. A total of 203 patients were evaluated for clonal B and T
Memon, Sadaf
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Monoclonal B-cell lymphocytosis
, 2019 International audienceFlow cytometry diagnostic practices can detect very low levels of clonal B cells in the peripheral blood. In the absence of clinical symptoms, cytopenia or organomegaly, the small clones may correspond to monoclonal B-cell leukemia (
Maitre, Elsa, Troussard, Xavier
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, 2007 The 2007 IWCLL guidelines indicate that a diagnosis of Chronic Lymphocytic Leukemia (CLL) requires a B-cell count above 5,000/μL in the absence of other features; below this level the diagnosis is Monoclonal B-cell Lymphocytosis (MBL).
Plummer, Marieth +10 more
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