Results 161 to 170 of about 16,334 (217)
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Neuropathy and monoclonal gammopathy
Current Opinion in Neurology, 2001The association of neuropathy with monoclonal gammopathy has been known for several years, even if the nosological position of these neuropathies is still debated. Similarly unsettled is the pathogenetic role and diagnostic relevance in clinical practice of the antineural antibodies frequently associated with monoclonal gammopathies of undetermined ...
E. Nobile-Orazio, M. Carpo
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Monoclonal Gammopathies and the Kidney
Annual Review of Medicine, 1989The major causes of renal insufficiency, present initially in half of the patients with multiple myeloma, are "myeloma kidney" and hypercalcemia. There is no reliable evidence that the isoelectric point (pI) or the type of light chain has an important role in renal failure.
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An acute monoclonal gammopathy?
Annales de biologie clinique, 2015Serum protein electrophoresis is commonly used in case of acute or chronic renal failure. It can lead to the etiologic diagnosis by detecting monoclonal gammopathies which are frequently complicated by renal failure, such as cast nephropathy, Randall's disease or amyloidosis, or to explore an associated inflammatory syndrome.
Alexandra, Presle +5 more
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Monoclonal gammopathy and neuropathy
Current Opinion in Neurology, 2009The management of peripheral neuropathy associated with monoclonal gammopathies has been advanced by recent clinical studies. We review the causal association between monoclonal gammopathy and neuropathy, and critically review the recent evidence on treatment.IgM monoclonal gammopathy of undetermined significance (MGUS) is the most commonly found ...
Sindhu, Ramchandren, Richard A, Lewis
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Autoantibodies in Patients with Monoclonal Gammopathies
Annals of the New York Academy of Sciences, 2007Abstract: Although autoantibody activities are rather often associated to monoclonal gammopathies, only monoclonal immunoglobulins of the IgM isotype are really directed against autoantigens that are often polysaccharides or are formed by highly repetitive structures. This strict association is frequently revealed also by clinical manifestations of the
CARLIZZI, guglielmo +7 more
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The Monoclonal Gammopathies (Paraproteins)
1990Publisher Summary This chapter discusses the pathogenesis of monoclonal gammopathies, including their cause, animal models, and role of T and B lymphocytes, cytogenetic aspects, and molecular biology. It focusses on the recognition of monoclonal proteins in the clinical chemistry laboratory, and a practical classification of the monoclonal ...
R A, Kyle, J A, Lust
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Monoclonal Gammopathy of Undetermined Significance
British Journal of Haematology, 2005SummarySignificant advances have been made in our understanding of the natural history, pathogenesis, mechanisms of progression and prognosis of monoclonal gammopathy of undetermined significance (MGUS). Although the overall incidence of MGUS progression is 1 per year, it is now possible to more accurately predict the risk of progression based on a new
Robert A, Kyle, S Vincent, Rajkumar
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Neuropathies associated with monoclonal gammopathies
Neuromuscular Disorders, 1996Abstract Searching for the presence of a monoclonal protein (also called paraprotein, monoclonal gammopathy, or M-protein) has become an important part of evaluating patients with chronic peripheral neuropathies of unknown cause. Approximately 10% of idiopathic neuropathy patients have an associated monoclonal gammopathy.
J T, Kissel, J R, Mendell
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Polyneuropathy and benign monoclonal gammopathy
Clinical Neurology and Neurosurgery, 1983Recently the rather frequent occurrence of benign monoclonal gammopathy (BMG) has been reported in peripheral neuropathy. Sometimes this syndrome is part of a multisystemic disorder in which organomegaly, endocrine disturbances, skin changes and focal bone lesions may also occur.
HOOGSTRATEN, MC +3 more
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Monoclonal Gammopathy in Lymphoma
Archives of Internal Medicine, 1975Serum protein electrophoresis was performed in 68% of 1,682 consecutive patients with lymphoma. Of 400 patients with chronic lymphocytic leukemia and lymphocytic lymphoma, 2.3% had an IgG peak, a frequency significantly higher than that found in normal individuals of comparable age. IgM peaks occurred in 4.5% of patients with lymphomas characterized by
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