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Monoclonal gammopathy and neuropathy
Current Opinion in Neurology, 1996There is a known coexistence between polyneuropathy and monoclonal gammopathy (immunoglobulin M, immunoglobulin G, immunoglobulin A). Antibodies to several glycoconjugates of the peripheral nervous system have been found in 50-65% of patients with immunoglobulin M monoclonal proteins, and distinct clinical syndromes have been recognized. However, if no
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Neuropathy and monoclonal gammopathy
2013The association of neuropathy with monoclonal gammopathy has been known for several years, even if the clinical and pathogenetic relevance of this association is not completely defined. This is not a marginal problem since monoclonal gammopathy is present in 1-3% of the population above 50 years in whom it is often asymptomatic, and in at least 8% of ...
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Archives of Internal Medicine, 1982
SCOT Hickman, MD, Assistant Professor in Medicine, Washington University School of Medicine, St Louis: A 73-year-old man was referred to the hematology clinic in January 1979 for evaluation of hyperglobulinemia detected at a routine visit to his private physician. The serum total protein level at that time was 9.1 g/dL with an albumin level of 4.4 g/dL.
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SCOT Hickman, MD, Assistant Professor in Medicine, Washington University School of Medicine, St Louis: A 73-year-old man was referred to the hematology clinic in January 1979 for evaluation of hyperglobulinemia detected at a routine visit to his private physician. The serum total protein level at that time was 9.1 g/dL with an albumin level of 4.4 g/dL.
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Monoclonal Gammopathy of Undetermined Significance
The American Journal of Medicine, 1978Monoclonal gammopathy of undetermined significance (MGUS) accounted for 56% of the 1026 patients with a monoclonal plasma cell disorder seen at the Mayo Clinic during 1992. Approximately 3% of persons older than 70 years and 1% of those older than 50 years had MGUS.
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'Benign' Monoclonal Gammopathy
JAMA, 1984A series of 241 patients with monoclonal protein but no evidence of multiple myeloma, macroglobulinemia, amyloidosis, or lymphoma (benign monoclonal gammopathy) were followed up for more than ten years. The patients were classified as follows: group 1, patients without increase of monoclonal serum protein during follow-up (benign) (37%); group 2 ...
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Ugeskrift for laeger, 2021
Monoclonal gammopathies range from benign conditions to severe malignancies. A summary is given in this review. Overall, the prevalence is high; monoclonal gammopathies (MGUS) occur in > 3% of persons above 50 years of age. Approximately 400 new cases of multiple myeloma and 80 new cases of amyloid light-chain (AL) amyloidosis are diagnosed yearly in ...
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Monoclonal gammopathies range from benign conditions to severe malignancies. A summary is given in this review. Overall, the prevalence is high; monoclonal gammopathies (MGUS) occur in > 3% of persons above 50 years of age. Approximately 400 new cases of multiple myeloma and 80 new cases of amyloid light-chain (AL) amyloidosis are diagnosed yearly in ...
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La Revue du praticien, 2006
Monoclonal gammopathies can induce clinical or biological symptoms, independent of any associated hemopathy. Cryoglobulins types I and II are responsible for cutaneous lesions, peripheral neuropathy, and membranoproliferative glomerulopathy. Peripheral neuropathies associated with monoclonal gammopathy are chronic, distal, symmetrical and progressive ...
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Monoclonal gammopathies can induce clinical or biological symptoms, independent of any associated hemopathy. Cryoglobulins types I and II are responsible for cutaneous lesions, peripheral neuropathy, and membranoproliferative glomerulopathy. Peripheral neuropathies associated with monoclonal gammopathy are chronic, distal, symmetrical and progressive ...
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