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Monoclonal gammopathy of undetermined significance [PDF]
Canadian Medical Association Journal, 2013 The condition, also known as benign monoclonal gammopathy, is characterized by the presence of a monoclonal immunoglobulin or light chain on immunofixation of the patient’s serum or urine.[1][1],[2][2] Such a diagnosis can only be considered if underlying causes, most notably multiple myeloma ...
Anguille, Sébastien, Bryant, Christian
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Monoclonal gammopathy of undetermined significance [PDF]
Blood, 2019 Abstract Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant plasma cell dyscrasia that consistently precedes multiple myeloma (MM) with a 1% risk of progression per year. Recent advances have improved understanding of the complex genetic and immunologic factors that permit progression from the aberrant plasma ...
Tarek H, Mouhieddine +2 more
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Overview of monoclonal gammopathies of undetermined significance [PDF]
British Journal of Haematology, 2007 SummaryAmong the B‐cell lymphoproliferative disorders, monoclonal gammopathy of undetermined significance (MGUS) is the humoral counterpart to monoclonal B‐cell lymphocytosis. This review introduces the papers from the section devoted to MGUS at the International Workshop entitled ‘Monoclonal B‐cell lymphocytosis and chronic lymphocytic leukaemia ...
Robert F, Vogt, Gerald E, Marti
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Nephrology Dialysis Transplantation, 2018 AbstractMonoclonal gammopathy of renal significance (MGRS) has introduced a new perspective to several well-known disease entities impacting nephrology, haematology and pathology. Given the constantly changing disease spectrum of these entities, it is clinically imperative to establish diagnostic and treatment pathways supported by evidence-based ...
Krzysztof, Batko +10 more
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Monoclonal gammopathy of undetermined significance-associated scleromyxoedema
Indian Dermatology Online Journal, 2019 Scleromyxoedema is a rare generalized cutaneous mucinosis, which in absence of thyroid disease, occurs almost invariably in patients with monoclonal gammopathies. A 54-year-old female patient presented with complaint of tightening of skin on the extremities, abdomen, forehead, gradually progressive since 1 year, episodes of generalized tonic-clonic ...
Kalgi D Baxi +3 more
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Monoclonal Gammopathy of Undetermined Significance
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2017 Objective: To determine follow-up practice patterns of US patients with monoclonal gammopathy of undetermined significance (MGUS) and their concordance with 4 clinical practice guidelines. Patients and Methods: In a retrospective analysis of adult patients using the OptumLabs Data Warehouse database, we identified those who had an incident diagnosis of
Ronald S. Go, MD +4 more
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Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2019 Monoclonal gammopathy of undetermined significance (MGUS) is one of the most prevalent premalignant conditions associated with a risk of malignant transformation to multiple myeloma (MM) or other forms of lymphoproliferative disorders with risk of progression of approximately 1% per year.
Sandecká, Viera +6 more
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The significance of monoclonal gammopathy of undetermined significance
Haematologica, 2009 Monoclonal gammopathy of undetermined significance (MGUS) is characterized by a serum M protein concentration of less than 30 g/L, fewer than 10% clonal plasma cells in the bone marrow, and the absence of end-organ damage that can be attributed to the plasma cell proliferative disorder.
Robert A. Kyle, Shaji Kumar
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[Monoclonal gammopathies of undetermined significance].
Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2009 Monoclonal gammopathy of undetermined significance (MGUS) is the most common type of monoclonal gammopathies. Genetic changes, various cytokines and bone marrow angiogenesis play an important role in the pathogenesis. As far as the malignant transformation of MGUS is concerned, size and type of the serum M-protein, serum kappa and lambda free light ...
V, Krizalkovicová +4 more
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A Comprehensive Review of Monoclonal Gammopathy of Undetermined Significance. [PDF]
J Adv Pract OncolNoonan K +5 more
europepmc +1 more source