Results 41 to 50 of about 145,799,037 (198)

Diagnosis of monoclonal gammopathy of renal significance

, 2015
Monoclonal gammopathy of renal significance (MGRS) regroups all renal disorders caused by a monoclonal immunoglobulin (MIg) secreted by a nonmalignant B-cell clone.
Fernando C. Fervenza, Kyle, R. A., Sanjeev Sethi, Angela Dispenzieri, Guillermo A. Herrera, Dispenzieri, A., Nelson Leung, Jean-Paul Fermand, Samih H. Nasr, Fermand, J. P., Picken, M. M., Murielle Roussel, Hutchison, C. A., International, Kidney, Bridoux, F., Efstathios Kastritis, Leung, N., Touchard, G., Sethi, S., Nasr, S. H., Roussel, M., MERLINI, GIAMPAOLO, Monoclonal Gammopathy Research, Group, Giampaolo Merlini, Herrera, G. A., Robert A. Kyle, Fervenza, F. C., Frank Bridoux, Guy Touchard, Kastritis, E., Colin A. Hutchison, Maria M. Picken   +31 more
core   +2 more sources

CD117 expression in gammopathies is associated with an altered maturation of the myeloid and lymphoid hematopoietic cell compartments and favorable disease features

Haematologica, 2011
Aberrant CD117 expression is associated with a favorable outcome in multiple myeloma. We analyzed 106 patients with symptomatic multiple myeloma (n=50), smoldering multiple myeloma (n=38) and monoclonal gammopathy of undetermined significance (n=18) to ...
Martin Schmidt-Hieber, Martin Pérez-Andrés, Bruno Paiva, Juan Flores-Montero, Jose J. Perez, Norma C. Gutierrez, Maria-Belen Vidriales, Sergio Matarraz, Jesus F. San Miguel, Alberto Orfao   +9 more
doaj   +1 more source

Kidney Transplantation and Monoclonal Gammopathy of Undetermined Significance

Transplantation Direct, 2021
Plasma cell disorders are one of the most common hematologic malignancies. Monoclonal gammopathy of undetermined significance (MGUS) is defined by a serum monoclonal protein
Nabeel Aslam, MD, Christopher L. Trautman, MD, Taimur Sher, MD   +2 more
doaj   +1 more source

Waldenstrom's macroglobulinemia in geriatric practice

Российский журнал гериатрической медицины, 2022
Using the clinical case of Waldenstrom's macroglobulinemia in an older patient, a research was carried out to find an algorithm for diagnosing the disease in patients of advance age, whose frequent polymorbid pathology makes it difficult to diagnose and ...
A. K. Ilyushchenko, L. V. Matchekhina
doaj   +1 more source

Upregulation of Dicer is more frequent in monoclonal gammopathies of undetermined significance than in multiple myeloma patients and is associated with longer survival in symptomatic myeloma patients

Haematologica, 2011
Dicer and Drosha are key enzymes in the miRNA-processing pathway which is altered in many human cancers.We analyzed Dicer and Drosha expression levels by quantitative PCR in 151 patients with monoclonal gammopathies: 102 symptomatic myeloma patients, 23 ...
María E. Sarasquete, Norma C. Gutiérrez, Irena Misiewicz-Krzeminska, Bruno Paiva, María C. Chillón, Miguel Alcoceba, Ramón García-Sanz, Jesús M. Hernández, Marcos González, Jesús F. San-Miguel   +9 more
doaj   +1 more source

Timing of acquisition of deletion 13 in plasma cell dyscrasias is dependent on genetic context

Haematologica, 2009
Background Multiple myeloma, monoclonal gammopathy of undetermined significance and smoldering multiple myeloma harbor common chromosomal abnormalities but the prevalence and relative association of aberrations in these diagnostic groups remains ...
Laura Chiecchio, Gian Paolo Dagrada, Ashraf H. Ibrahim, Elizabet Dachs Cabanas, Rebecca K.M. Protheroe, David M. Stockley, Kim H. Orchard, Nicholas C.P. Cross, Christine J. Harrison, Fiona M. Ross   +9 more
doaj   +1 more source

Prevalence of transthyretin cardiac amyloidosis in undifferentiated heart failure with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 1176-1182, April 2025.
Abstract Aims Transthyretin amyloid cardiomyopathy (ATTR‐CM) is an increasinglyrecognized cause of heart failure with preserved ejection fraction (HFpEF), which may be diagnosed non‐invasively using 99mTc 3,3‐diphosphono‐1,2‐propanodicarboxylic acid (DPD) scintigraphy‐based diagnostic criteria.
L. Healy, G. Giblin, A. Gray, N. Starr, L. Murphy, D. O'Sullivan, E. Kavanagh, C. Howley, C. Tracey, E. Morrin, A. McDaid, A. Clarke, J.O. O'Neill, E. Joyce, M. O'Connell, N. G. Mahon   +15 more
wiley   +1 more source

The clinical implication of monoclonal gammopathies: monoclonal gammopathy of undetermined significance and of renal significance

Nephrology Dialysis Transplantation, 2018
AbstractMonoclonal gammopathy of renal significance (MGRS) has introduced a new perspective to several well-known disease entities impacting nephrology, haematology and pathology. Given the constantly changing disease spectrum of these entities, it is clinically imperative to establish diagnostic and treatment pathways supported by evidence-based ...
Krzysztof, Batko, Jolanta, Malyszko, Artur, Jurczyszyn, David H, Vesole, Morie A, Gertz, Xavier, Leleu, Anna, Suska, Marcin, Krzanowski, Władysław, Sułowicz, Jacek S, Malyszko, Katarzyna, Krzanowska   +10 more
openaire   +3 more sources

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Impact of hematologic complete response in the treatment of sporadic late‐onset nemaline myopathy associated with monoclonal gammopathy

Clinical Case Reports, 2021
Monoclonal gammopathy of undetermined significance (MGUS) may be associated with pathologies with severe neuromuscular manifestations such as sporadic late‐onset nemaline myopathy (SLONM).
Tânia Maia, Rui Bergantim, Henrique Costa, Jorge Pinheiro, Fernanda Trigo   +4 more
doaj   +1 more source