Results 31 to 40 of about 13,966 (231)

Autoimmunity, Infections, and the Risk of Monoclonal Gammopathy of Undetermined Significance

Frontiers in Immunology, 2022
Various epidemiological studies, including case reports and -series in addition to larger, population-based studies, have reported an increased prevalence of monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma in individuals ...
Aðalbjörg Ýr Sigurbergsdóttir, T. Love, S. Kristinsson   +2 more
semanticscholar   +1 more source

Body mass index associated with monoclonal gammopathy of undetermined significance (MGUS) progression in Olmsted County, Minnesota

Blood Cancer Journal, 2022
Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant clonal disorder that progresses to multiple myeloma (MM), or other plasma-cell or lymphoid disorders at a rate of 1%/year.
G. Kleinstern, D. Larson, C. Allmer, A. Norman, Grace Muntifering, J. Sinnwell, A. Visram, V. Rajkumar, A. Dispenzieri, R. Kyle, S. Slager, Shaji K. Kumar, C. Vachon   +12 more
semanticscholar   +1 more source

Monoclonal gammopathy associated with visceral leishmaniasis

Brazilian Journal of Infectious Diseases, 2010
Monoclonal gammopathy can accompany diverse conditions and is usually benign. It should be distinguished from monoclonal gammopathy of undetermined significance (MGUS) which can rarely turn malignant.
Vishal Sharma, MD, Mukul P. Agarwal, MD, Subhash Giri, MD   +2 more
doaj   +1 more source

Monoclonal Gammopathy of Undetermined Cardiovascular Significance; Current Evidence and Novel Insights

Journal of Cardiovascular Development and Disease, 2023
Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant condition characterized by the presence of low levels of a monoclonal protein in the serum and a low percentage of clonal plasma cells in the bone marrow.
A. Tentolouris, I. Ntanasis-Stathopoulos, M. Gavriatopoulou, I. Andreadou, E. Terpos   +4 more
semanticscholar   +1 more source

CD117 expression in gammopathies is associated with an altered maturation of the myeloid and lymphoid hematopoietic cell compartments and favorable disease features

Haematologica, 2011
Aberrant CD117 expression is associated with a favorable outcome in multiple myeloma. We analyzed 106 patients with symptomatic multiple myeloma (n=50), smoldering multiple myeloma (n=38) and monoclonal gammopathy of undetermined significance (n=18) to ...
Martin Schmidt-Hieber, Martin Pérez-Andrés, Bruno Paiva, Juan Flores-Montero, Jose J. Perez, Norma C. Gutierrez, Maria-Belen Vidriales, Sergio Matarraz, Jesus F. San Miguel, Alberto Orfao   +9 more
doaj   +1 more source

Monoclonal gammopathy of undetermined significance: evaluation, risk assessment, management, and beyond

Faculty Reviews, 2022
Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant state for a spectrum of lymphoplasmacytic malignancies. The risk of progression of MGUS to a symptomatic therapy requiring plasma cell dyscrasia is about 1% per year.
J. Abeykoon, R. Tawfiq, Shaji K. Kumar, S. Ansell   +3 more
semanticscholar   +1 more source

The spectrum of somatic mutations in monoclonal gammopathy of undetermined significance indicates a less complex genomic landscape than that in multiple myeloma

Haematologica, 2017
Monoclonal gammopathy of undetermined significance is a pre-malignant precursor of multiple myeloma with a 1% risk of progression per year. Although targeted analyses have shown the presence of specific genetic abnormalities such as IGH translocations ...
Aneta Mikulasova, Christopher P. Wardell, Alexander Murison, Eileen M. Boyle, Graham H. Jackson, Jan Smetana, Zuzana Kufova, Ludek Pour, Viera Sandecka, Martina Almasi, Pavla Vsianska, Evzen Gregora, Petr Kuglik, Roman Hajek, Faith E. Davies, Gareth J. Morgan, Brian A. Walker   +16 more
doaj   +1 more source

Waldenstrom's macroglobulinemia in geriatric practice

Российский журнал гериатрической медицины, 2022
Using the clinical case of Waldenstrom's macroglobulinemia in an older patient, a research was carried out to find an algorithm for diagnosing the disease in patients of advance age, whose frequent polymorbid pathology makes it difficult to diagnose and ...
A. K. Ilyushchenko, L. V. Matchekhina
doaj   +1 more source

Prognosis of young patients with monoclonal gammopathy of undetermined significance (MGUS)

Blood Cancer Journal, 2021
Monoclonal gammopathy of undetermined significance (MGUS) is rare in young patients (age
L. Pang, S. Rajkumar, P. Kapoor, F. Buadi, A. Dispenzieri, M. Gertz, M. Lacy, R. Kyle, Shaji K. Kumar   +8 more
semanticscholar   +1 more source

Monoclonal Gammopathy of Undetermined Significance Disguised as Chronic Neutrophilic Leukemia

Mediterranean Journal of Hematology and Infectious Diseases, 2010
A 60-year-old woman with a medical history of diabetes mellitus, osteoporosis, peripheral vascular disease, and hypertension who was otherwise asymptomatic but continued showing elevated neutrophil levels sought a second opinion at our facility.
Monique A Hartley-Brown, Lubomir Sokol, Gisela L Caceres, Mohammed A Hussein, Alan List, Javier Pinilla-Ibarz   +5 more
doaj   +3 more sources