Results 91 to 100 of about 124,968 (208)

In vivo tracking and immunological properties of pulsed porcine monocyte-derived dendritic cells [PDF]

, 2015
Cellular therapies using immune cells and in particular dendritic cells (DCs) are being increasingly applied in clinical trials and vaccines. Their success partially depends on accurate delivery of cells to target organs or migration to lymph nodes ...
Benitez-Ribas, Daniel, Bárcena, Juan, Cabezón, Raquel, Crisci, Elisa, Córdoba, Lorena, Espada, Yvonne, Fraile Sauce, Lorenzo José, Martínez, Jorge, Montoya, Maria, Novellas, Rosa   +9 more
core   +2 more sources

Phase 1 Trial of Vaccination with Autologous Tumor Cells and Antisense Directed Against the Insulin Growth Factor Type 1 Receptor (IGF-1R AS ODN) in Patients with Recurrent Glioblastoma [PDF]

, 2018
Background: Extending a previous Phase I study, we report the results of a second Phase I autologous tumor cell vaccination trial for patients with recurrent glioblastomas (IND 14379-101, NCT01550523). Methods: Following surgery, subjects were treated by
Andrews MD, David W., Harshyne, PhD, Larry, Hooper, PhD, D. Craig, Judy, MD, Kevin   +3 more
core   +2 more sources

Cognitive impairment and elevated neutrophil-to-lymphocyte ratio and monocyte-to-lymphocyte ratio in schizophrenia

East Asian Archives of Psychiatry
The efficacy of current schizophrenia treatments on cognitive symptoms remains limited owing to constrained data around the aetiopathogenesis of such symptoms. Complete blood cell counts have been used to identify variations in inflammatory responses among individuals with schizophrenia.
R, Syahna, M M, Amin, V, Camellia, E, Effendy, Z, Yamamoto   +4 more
openaire   +2 more sources

TLR7-mediated skin inflammation remotely triggers chemokine expression and leukocyte accumulation in the brain [PDF]

, 2016
Background: The relationship between the brain and the immune system has become increasingly topical as, although it is immune-specialised, the CNS is not free from the influences of the immune system.
A Boivin, A Constant, A Walter, AD Bachstetter, Alison McColl, B Winner, BT Fife, C Callewaere, C D'Mello, C Gemma, CA Thomson, Carolyn A. Thomson, CP Marques, CS McKimmie, CT Ekdahl, D Michlmayr, D Michlmayr, EE Ubogu, G Banisadr, G Banisadr, Gerard J. Graham, JH Dufour, JL Teeling, Jonathan Cavanagh, JS Cameron, JS Snyder, JT Rogers, L Azzi, L Cartier, L Fits van der, Louis Nerurkar, M Baggiolini, M Udina, ML Monje, MM Lee, N Andrews, Q Liu, R Dantzer, R Deacon, R Krishnan, R Rola, RM Deacon, RM Ransohoff, S Baraldi, S Goethals, S Potvin, S Tyring, SM O'Brien, U Patel, U Puntener, W Huang da, W Huang da, W Rostene, WJ Karpus   +53 more
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Daily Preventive Zinc Supplementation Decreases Lymphocyte and Eosinophil Concentrations in Rural Laotian Children from Communities with a High Prevalence of Zinc Deficiency: Results of a Randomized Controlled Trial. [PDF]

, 2020
BACKGROUND:Zinc deficiency impairs immune function and is common among children in South-East Asia. OBJECTIVES:The effect of zinc supplementation on immune function in young Laotian children was investigated.
Andreini, Anzilotti, Barffour, Beck, Black, Boulay, Brown, Butt, Castillo-Duran, Charles B Stephensen, Chidchamai Kewcharoenwong, Gammoh, Ganjana Lertmemongkolchai, Gertrud U Schuster, Gibson, Guy-Marino Hinnouho, Haase, Hojyo, Honscheid, International Zinc Nutrition Consultative Group, International Zinc Nutrition Consultative Group, Inthira Tussakhon, Janet M Peerson, Jia, K Ryan Wessells, Kenneth H Brown, King, Lu, Maizels, Maxwell A Barffour, Mayo-Wilson, Maywald, Mehta, Prasad, Rajamanickam, Raqib, Ravin, Richter, Rosenkranz, Rosenkranz, Sandstead, Sazawal, Sengchanh Kounnavong, Sheikh, Shi, Sonja Y Hess, Tahan, Tepaamorndech, Walker, Wan, Waraporn Samer, Wessells, Wessells, WHO, Wu   +54 more
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Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response. [PDF]

, 2019
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and confers a poor prognosis. Beyond standard systemic therapy with multikinase inhibitors, recent studies demonstrate the potential for robust and durable responses ...
Fong, Lawrence, Keenan, Bridget P, Kelley, Robin K   +2 more
core   +2 more sources

Monocyte to lymphocyte blood ratio in tuberculosis and HIV patients: Comparative analysis, preliminary data [PDF]

, 2017
Recent data confirmed the hypothesis suggested by historical studies that the ratio of peripheral blood monocytes to lymphocytes (M/L) is associated with the risk of tuberculosis (TB) disease.
Ciaccio, M., Colomba, C., Di Carlo, P., Giammanco, A., Guadagnino, G., Mililli, D., Scarlata, F., Serra, N.   +7 more
core  

Preoperative Lymphocyte-Monocyte Ratio Ameliorates the Accuracy of Differential Diagnosis in Non-Metastatic Infiltrative Renal Masses [PDF]

, 2017
Purpose: Distinguishing infiltrative renal cell carcinoma (RCC) from transitional cell carcinoma (TCC) is a challenging issue due to their radiologic similarities. We evaluated systemic inflammatory biomarkers as parameters for distinguishing tumor types.
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core   +1 more source

Relationship between monocyte-to-lymphocyte ratio and anemia: a NHANES analysis

Hematology
Growing evidence supports the significant role of inflammatory factors in anemia. This paper intends to ascertain the potential link between MLR and anemia and explore potential mediators. Our analysis employed comprehensive data recourse from the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2018 utilizing weighted logistic ...
Yongjin Zhi, Shuojing Bao, Jingcheng Mao, Hui Zhu, Jianfeng Zhu   +4 more
openaire   +2 more sources

The prognostic value of preoperative peripheral blood inflammatory biomarkers in extrahepatic cholangiocarcinoma: a systematic review and meta-analysis

Frontiers in Oncology
BackgroundRecent evidence indicates that inflammation plays a major role in the pathogenesis and progression of CCA. This meta-analysis seeks to evaluate the prognostic implications of preoperative inflammatory markers, specifically NLR, PLR, and LMR, in
Di Zeng, Di Zeng, Yaoqun Wang, Yaoqun Wang, Ningyuan Wen, Ningyuan Wen, Jiong Lu, Jiong Lu, Bei Li, Bei Li, Nansheng Cheng, Nansheng Cheng   +11 more
doaj   +1 more source