Results 141 to 150 of about 623,154 (347)

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu   +4 more
wiley   +1 more source

Hexokinase 3 Dysfunction Promotes Tumorigenesis and Immune Escape by Regulating Monocyte/Macrophage Infiltration of Clear Cell Renal Cell Carcinoma Microenvironment

open access: green, 2021
Wenhao Xu   +11 more
openalex   +1 more source

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

open access: yesAdvanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez   +4 more
wiley   +1 more source

Hepatitis B surface antigen impairs TLR4 signaling by upregulating A20 expression in monocytes

open access: yesMicrobiology Spectrum
Toll-like receptors (TLRs) play a crucial role in eliminating viral infection. Conversely, viruses have evolved various strategies to disrupt TLR signaling during chronic infection.
Cong Wang   +6 more
doaj   +1 more source

Engagement of CD14 on human monocytes terminates T cell proliferation by delivering a negative signal to T cells [PDF]

open access: bronze, 1991
Ko‐Huang Lue   +4 more
openalex   +1 more source

Monocytes warning for malaria

open access: green, 2023
Nada Riahi   +5 more
openalex   +2 more sources

Safe and Localized Lentiviral Gene Delivery via Injectable Mesoporous Scaffolds for Potent Antitumor Immunity

open access: yesAdvanced Materials, EarlyView.
This work introduces an injectable mesoporous silica rod scaffold that confines lentiviral vectors to the injection site, enabling localized dendritic cell recruitment and transduction. The platform sustains antigen expression, promotes robust T‐cell activation, and enhances antitumor immunity.
Thanh Loc Nguyen   +12 more
wiley   +1 more source

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