Results 171 to 180 of about 400,128 (308)

Inflammatory Monocytes Recruited to the Liver within 24 Hours after Virus-Induced Inflammation Resemble Kupffer Cells but Are Functionally Distinct [PDF]

, 2015
Dowty Movita, Martijn D. B. van de Garde, Paula J. Biesta, Kim Kreefft, Bart L. Haagmans, Elina I. Zúñiga, Florence Herschke, Sandra De Jonghe, Harry L.A. Janssen, Lúcio Gama, André Boonstra, Thomas Vanwolleghem   +11 more
openalex   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Predictive potential of patient-specific immunological characteristics in solid cancers: circulating monocytes, myeloid-derived suppressor cells, T cells, and the T-cell receptor repertoire. [PDF]

ESMO Open
Zierfuss C, Niederdorfer B, Fendl B, Syböck K, Schedl J, Kohl L, Heller G, Tomasich E, Berger JM, Sunder-Plassmann V, Kleinberger M, Gottmann L, Korpan M, Starzer AM, Solano Henao I, Fürst J, Wolfsberg J, Grohmannova M, Dobrovits N, Ay C, Vladic N, Furtner J, Preusser M, Berghoff AS.   +23 more
europepmc   +1 more source

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

Advanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Zhe Chen, Xiaodian Cai, Haonan Zeng, Zhonghao Bai, Jinghui Li, Xiangchun Pan, Leyan Yan, Fei Wang, Lin Lin, Yonglun Luo, Goutam Sahana, Mogens Sandø Lund, Maria Ballester, Daniel Crespo‐Piazuelo, Peter Karlskov‐Mortensen, Merete Fredholm, Alex Clop, Marcel Amills, Crystal Loving, Christopher K. Tuggle, Ole Madsen, Jiaqi Li, Zhe Zhang, George E. Liu, Jicai Jiang, Lingzhao Fang, Guoqiang Yi   +31 more
wiley   +1 more source

Exploring the association between complete blood cell count-derived inflammatory biomarkers and cancer incidence through interpretable machine learning models: A study based on NHANES 1999 to 2016. [PDF]

Medicine (Baltimore)
Zhao S, Fu P, Lin L, Zhou H, Huang Y, Li Y, Tang C.   +6 more
europepmc   +1 more source

Activity of interleukin 6 in the differentiation of monocytes to macrophages and dendritic cells [PDF]

, 2000
Hidetsugu Mitani, Naoyuki Katayama, Hiroto Araki, K Ohishi, Kyoko Kobayashi, Hirohito Suzuki, Kazuhiro Nishii, Masahiro Masuya, Kiyoshi Yasukawa, Nobuyuki Minami, Hiroshi Shiku   +10 more
openalex   +1 more source

T Cell Glycoengineering to Modulate Immune‐Tumor Crosstalk: A Universal Non‐Genetic Strategy for Enhanced Tumor Immunotherapy

Advanced Science, EarlyView.
This study describes a T cell surface engineering strategy that integrates polymer materials with tumor immunology, aiming to achieve broad‐spectrum anti‐tumor applications of glycopolymer‐engineered T (G‐T) cells via non‐genetic modification. Glycopolymer engineering generally modulates immune‐tumor crosstalk through specific cell‐cell interactions ...
Lihua Yao, He Yang, Fangjian Shan, Xiaomeng Niu, Yichen Wang, Hengyuan Zhang, Sujian Wang, Gaojian Chen, Hong Chen   +8 more
wiley   +1 more source

The role of interferon-mediated suppression of monocyte immunothrombosis in infection susceptibility in systemic lupus erythematosus. [PDF]

Clin Exp Immunol
Murphy FK, Yennemadi AS, Jordan N, Leisching G.   +3 more
europepmc   +1 more source

Toll like receptor agonists augment HPV 11 E7-specific T cell responses by modulating monocyte-derived dendritic cells [PDF]

, 2009
Xianzhen Chen, Xiaohong Mao, Kejian Zhu, Na Jin, Jun Ye, Jian-Ping Cen, Qiang Zhou, Hao Cheng   +7 more
openalex   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source