Results 191 to 200 of about 623,154 (347)

Monocytes from inflammatory arthritis patients accumulate methotrexate and their transcriptome predicts methotrexate clinical response. [PDF]

Cell Mol Life Sci
Ríos I, Schiaffino MT, López-Navarro B, Triguero-Martínez A, Lin M, Torres-Torresano M, Struys EA, Álvarez S, Román M, Abad-Santos F, Castañeda S, Garcia-Castañeda N, de Jonge R, Jansen G, Castrejón I, González-Álvaro I, Puig-Kröger A.   +16 more
europepmc   +1 more source

Author response: Single cell analysis reveals human cytomegalovirus drives latently infected cells towards an anergic-like monocyte state

, 2020
Miri Shnayder, Aharon Nachshon, Batsheva Rozman, Biana Bernshtein, Michael Lavi, Noam Fein, Emma Poole, Selmir Avdic, Emily Blyth, David Gottlieb, Allison Abendroth, Barry Slobedman, John Sinclair, Noam Stern‐Ginossar, Michal Schwartz   +14 more
openalex   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

The immunopathological crosstalk of diabetic periodontitis: Single-cell insights into monocyte dysregulation. [PDF]

PLoS One
Si C, Wu X, Cheng H, Jiang W, Yan H.
europepmc   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

INPP5D/SHIP1-mediated immunometabolic remodeling of renal monocytes in idiopathic membranous nephropathy. [PDF]

Front Immunol
Dai H, Liu B, Rui H, Yang L, Jiang H, Zhao Q, Liu W.   +6 more
europepmc   +1 more source

Calcium Oxalate Differentiates Human Monocytes Into Inflammatory M1 Macrophages [PDF]

, 2018
Paul R. Dominguez‐Gutierrez, Sergei Kusmartsev, Benjamin K. Canales, Saeed R. Khan   +3 more
openalex   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

Proteasomal-dependent endothelial P2Y₆ receptor downregulation as an adaptive mechanism limiting monocyte adhesion during intestinal schistosomiasis. [PDF]

Purinergic Signal
Oliveira NF, Monteiro MMLV, Crepaldi LD, Coutinho-Silva R, Savio LEB, Silva CLM.   +5 more
europepmc   +1 more source

Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1β [PDF]

, 2018
et al,, Gelman, Andrew E, Hsiao, Hsi-Min, Kreisel, Daniel, Lavine, Kory J, Li, Wenjun, Liu, Yongjian, Luehmann, Hannah P, Puri, Varun, Ruiz-Perez, Daniel, Scozzi, Davide, Spahn, Jessica H, Takahashi, Tsuyoshi, Tanaka, Satona, Turam, Cem   +14 more
core   +1 more source