Results 231 to 240 of about 712,808 (414)

Targeting Decidual CD16+ Immune Cells with Exosome‐Based Glucocorticoid Nanoparticles for Miscarriage

open access: yesAdvanced Science, EarlyView.
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang   +17 more
wiley   +1 more source

Effects of Microgravity on the Monocyte/Macrophage Physiology and the Potential Implication in Immune Responses to Vaccines

open access: yesVaccine Research, 2019
Introduction: Exposure to the microgravity environment could cause human physiological abnormalities that include fluid shift, anemia, osteoporosis, immunosuppression, etc. Monocytes and macrophages are important components of the immune system and could
Jiawei Yang, Wanlin Xing, Chongzhen Wang
doaj  

THE INTERACTION BETWEEN HUMAN MONOCYTES AND RED CELLS [PDF]

open access: bronze, 1970
Neil Abramson   +3 more
openalex   +1 more source

Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional Gjb2 Null Mice Model

open access: yesAdvanced Science, EarlyView.
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang   +8 more
wiley   +1 more source

Editorial: Monocyte heterogeneity and plasticity

open access: yesFrontiers in Immunology
Heather J. Medbury   +5 more
doaj   +1 more source

GRP78 Nanobody‐Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A GRP78 nanobody‐directed immunotoxin suppresses cancer progression and metastasis by enhancing antitumor immunity via STING pathway activation, offering a pan‐cancer‐targeted approach and immunotherapy combination strategy. Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies.
Huifang Wang   +16 more
wiley   +1 more source

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