Results 271 to 280 of about 712,808 (414)

Virus-associated inflammation imprints an inflammatory profile on monocyte-derived macrophages in the human liver. [PDF]

open access: yesJ Clin Invest
Sanchez Vasquez JD   +16 more
europepmc   +1 more source

Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis

open access: yesAdvanced Science, EarlyView.
Previous research suggests that AIP may prevent atherogenic foamy macrophage formation. This study reveals that AIP, via its chaperone interaction with AHR, inhibits p38‐c‐JUN‐mediated transactivation of HM13, which encodes the ERAD protease HM13/SPP. HM13/SPP promotes foamy macrophage formation in addition to atherogenesis and plaque foamy macrophage ...
Yu Cao   +15 more
wiley   +1 more source

Monocyte Conversion During Inflammation and Injury.

open access: yesArteriosclerosis, Thrombosis and Vascular Biology, 2017
Rachel M. Kratofil, P. Kubes, J. Deniset
semanticscholar   +1 more source

Tumoroid Model Reveals Synergistic Impairment of Metabolism by Iron Chelators and Temozolomide in Chemo‐Resistant Patient‐derived Glioblastoma Cells

open access: yesAdvanced Science, EarlyView.
This study investigates the metabolic vulnerabilities of glioblastoma (GBM), an aggressive brain tumor. Research demonstrates that iron chelation therapy, in combination with standard chemotherapy, significantly enhances the efficacy of treatment against resistant GBM cells in a 3D tumoroid model.
Meitham Amereh   +8 more
wiley   +1 more source

Integrative Multi‐Omics and Routine Blood Analysis Using Deep Learning: Cost‐Effective Early Prediction of Chronic Disease Risks

open access: yesAdvanced Science, EarlyView.
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong   +20 more
wiley   +1 more source

Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans

open access: yesCirculation, 2016
F. M. van der Valk   +17 more
semanticscholar   +1 more source

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