Results 341 to 350 of about 712,808 (414)

Human Monocyte Chemotaxis: A Quantitative in Vivo Technique

, 1979
David A. Norris, SUSAN H. LIPMAN, William L. Weston   +2 more
openalex   +1 more source

M2 Macrophage‐Derived Extracellular Vesicles Reprogram Immature Neutrophils into Anxa1hi Neutrophils to Enhance Inflamed Bone Regeneration

Advanced Science, EarlyView.
This study reveals that M2‐EVs mitigate periodontitis‐induced bone resorption by modulating neutrophil fate. Single‐cell RNA sequencing identified an Anxa1hi neutrophil subpopulation with pro‐reparative properties. M2‐EVs disrupt neutrophil maturation, promoting this subpopulation through key reprogramming genes (Acvrl1, Fpr2). These findings highlight
Yufei Yao, Yijia Yin, Fangyuan Shuai, Waishan Lam, Tao Zhou, Yaxin Xie, Xuesong He, Xianglong Han   +7 more
wiley   +1 more source

Predictive value of inflammatory indexes in in-hospital mortality for patients with acute aortic dissection. [PDF]

BMC Cardiovasc Disord
Xin Y, Lyu S, Wang J, Wang Y, Shu Y, Liang H, Yang Y.   +6 more
europepmc   +1 more source

IRF8 Drives Conventional Type 1 Dendritic Cell Differentiation and CD8+ T Cell Activation to Aggravate Abdominal Aortic Aneurysm Development

Advanced Science, EarlyView.
This study highlights the critical role of IRF8 in the development of AAA. IRF8 activation promotes the differentiation of cDC1s, which in turn recruit and activate CD8+ T cells, contributing to aortic wall degradation. The study identifies the IRF8‐cDC1‐CD8+ T cell axis as a key pathway in AAA progression, offering new potential therapeutic targets to
Zhen Yuan, Li Shu, Yidan Zheng, Yidong Wang, Mengsha Zheng, Jie Sun, Jiantao Fu, Zihao Zhou, Shen Song, Zhenjie Liu, Fei Li, Zhejun Cai   +11 more
wiley   +1 more source

Human Blood Monocyte Subsets: A New Gating Strategy Defined Using Cell Surface Markers Identified by Mass Cytometry

Arteriosclerosis, Thrombosis and Vascular Biology, 2017
G. Thomas, A. Hamers, Catherine Nakao, Paola M. Marcovecchio, Angela M Taylor, Chantel C McSkimming, A. Nguyen, C. McNamara, C. Hedrick   +8 more
semanticscholar   +1 more source

Robust Predictive Performance of MLPAS and CCMLP for Clinical Outcome and Risk Stratification in Patients with Colorectal Cancer. [PDF]

J Inflamm Res
Ye QY, Wang YY, Wang ZJ, Lu M, Peng HX, Wang X, Cheng XX, Ying HQ.   +7 more
europepmc   +1 more source

Electroactive Electrospun Nanofibrous Scaffolds: Innovative Approaches for Improved Skin Wound Healing

Advanced Science, EarlyView.
This review explores the potential of electroactive electrospun nanofibrous (EEN) scaffolds for enhanced skin wound healing. It discusses how a variety of electroactive materials can be prepared into EEN scaffolds via electrospinning technology, and their applications in various wound types. The review provides insights into the future perspectives for
Yang Zhang, Zhiyuan Zheng, Shilu Zhu, Liang Xu, Qingdong Zhang, Jie Gao, Min Ye, Shuwei Shen, Jinyu Xing, Ming Wu, Ronald X. Xu   +10 more
wiley   +1 more source

The immunosuppressive role of VSIG4 in colorectal cancer and its interaction with the tumor microenvironment. [PDF]

Discov Oncol
Zhang HG, Yao WR, Zhou ZY, Liu L.
europepmc   +1 more source

Halofuginone Disrupted Collagen Deposition via mTOR‐eIF2α‐ATF4 Axis to Enhance Chemosensitivity in Ovarian Cancer

Advanced Science, EarlyView.
COL1A1, a major component of ECM, contributes to chemoresistance and poor prognosis in ovarian cancer. Halofuginone (HF) attenuates CAF‐secreted COL1A1 through mTOR‐eIF2α‐ATF4 axis. Notably, HF disrupts collagen deposition to form the looser ECM and facilitates CD8+ T cell infiltration, partially via M2‐M1 macrophage polarization to enhance ...
Wenxin Li, Yenan Wu, Yanan Zhang, Wenyan Gao, Xin Li, Haixia Luo, Mengmeng Lu, Zhihua Liu, Aiping Luo   +8 more
wiley   +1 more source

Fibrosis factor CTGF facilitates VCAM‑1‑dependent monocyte adhesion to osteoarthritis synovial fibroblasts via the FAK and JNK pathways. [PDF]

Mol Med Rep
Liu SC, Law YY, Wu YY, Huang YL, Tsai CH, Chen WC, Tang CH.   +6 more
europepmc   +1 more source