Results 321 to 330 of about 940,972 (387)

Peptide-functionalized periodic mesoporous silica nanoparticles for monocyte-specific TET3 Silencing enhance cardiac repair after acute myocardial infarction. [PDF]

J Nanobiotechnology
Jin H, Ding J, Zhang X, Cheng S, Zhang Y, Wu Y, Liu C, Yang S, Zhang A, Ma G, Lu W.   +10 more
europepmc   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Exercise-induced histone lactylation in monocyte-derived macrophages restores cardiac immune homeostasis and function in sepsis-induced cardiomyopathy. [PDF]

Nat Commun
Sun S, Lai C, Huang C, Ren X, Zhang T, Zou J, Tong Y, Zhou Q, Lu J, Shen Z, Chen W, Wang R, Rabrenovic N, Wang X, Ma B, Qian J, Fu G, Shang M.   +17 more
europepmc   +1 more source

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

Advanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang, Ke‐Yu Zhang, Lang‐Jian Zhu, Wei‐Jue Li, Yang Wu, Xiang Gao, Xiao‐Ru Ma, Xiu‐Hua Yin, Jian‐Bin Wu, Xiao‐Kang Ye, Zhao‐Jun Dong, Di‐Xian Wang, Zhe Zhou, Shao‐Dong Wang, Lei Han, Zhi‐Nong Jiang, Jing‐Wei Zhao   +16 more
wiley   +1 more source

Alzheimer's Disease Risk Variants Interact with Amyloid-Beta to Modulate Monocyte Function. [PDF]

Cells
Chatila ZK, Bradshaw EM.
europepmc   +1 more source

Differential regulation of 5-lipoxygenase and leukotriene-C4-synthase expression by IFNγ, IL-4 and IL-13 in human monocytes and macrophages from patients with atopic dermatitis. [PDF]

Inflamm Res
Lietzau S, Traidl S, Riesselmann C, Werfel T, Mommert S.   +4 more
europepmc   +1 more source

A framework integrating multiscale in silico modeling and experimental data predicts CAR-NK cell cytotoxicity across target cell types. [PDF]

Proc Natl Acad Sci U S A
Ahmad S, Xing K, Pereira MSF, Castle S, Rajakaruna H, Nayak I, Stewart WC, Beckwith KA, Cairo MS, Naeimi Kararoudi M, Lee DA, Das J.   +11 more
europepmc   +1 more source

Correlation of Neutrophil to Lymphocyte Ratio (NLR) and Monocyte to Lymphocyte Ratio (MLR) in Diagnosis of Bacterial Infection in Children with Acute Febrile Illness - A Retrospective Descriptive Study

M Kruthi, S Nagajyothi, V. Muniyappa, Mansi Kumar   +3 more
openalex   +1 more source