Results 181 to 190 of about 272,971 (193)

Circulating levels of the pro-inflammatory monomeric isoform of C-reactive protein (mCRP) correlate with inflammatory markers in patients with stage II-III colon cancer.

Journal of Clinical Oncology, 2023
e15641 Background: Tumor-promoting inflammation is an established hallmark of cancer. C-reactive protein (CRP) is one of the most studied negative prognostic markers of the systemic inflammatory response (SIR) and known to be implicated in detrimental ...
Anniken Joerlo Fuglestad, P. Bousquet, A. H. Kostner, S. Meltzer, A. H. Ree, R. Fernandez-Botran, C. Kersten   +6 more
semanticscholar   +1 more source

Crp/fnr family protein binds to promoters of atxA and sodmn genes that regulate the expression of exotoxins in Bacillus anthracis.

Protein Expression and Purification, 2022
Bacillus anthracis produces a tripartite exotoxin, which is regulated by AtxA. Sodmn is constitutively expressed during invasion. Crp/Fnr family transcriptional regulators are known to bind promoters of toxin regulators as well as constitutively ...
D. Goel, Sudhir Kumar, G. Joshi, P. Rai, R. Bhatnagar   +4 more
semanticscholar   +1 more source

Microglial pro-inflammatory mechanisms induced by monomeric C-reactive protein are counteracted by soluble epoxide hydrolase inhibitors

International Immunopharmacology
Monomeric C-reactive protein (mCRP) is a pro-inflammatory molecule generated by the dissociation of native CRP. Clinical and experimental studies suggest that mCRP deposition in the brain induces Alzheimer’s disease (AD) pathology and cognitive loss ...
Clara Bartra, K. Vuraić, Yi Yuan, S. Codony, Haydeé Valdés-Quiroz, C. Casal, M. Slevin, Leonardo Máquez-Kisinousky, Anna M. Planas, C. Griñán-Ferré, Mercè Pallàs, C. Morisseau, B. D. Hammock, S. Vázquez, C. Suñol, C. Sanfeliu   +15 more
semanticscholar   +1 more source

FUNCTIONAL ACTIVITY OF MONOMERIC C-REACTIVE PROTEIN IN INTERVERTEBRAL DISC

Orthopaedic Proceedings
Monomeric C reactive protein (mCRP) presents important proinflammatory effects in endothelial cells, leukocytes, or chondrocytes. However, CRP in its pentameric form exhibits weak anti-inflammatory activity.
C. Ruiz-Fernández, D. A. Eldjoudi, M. González-Rodríguez, A.C. Barreal, Y. Farrag, A. Mobasheri, J. Pino, D. Sakai, O. Gualillo   +8 more
semanticscholar   +1 more source

Antibodies against monomeric CRP - a promising biomarker of lupus nephritis?

Nephrology Dialysis Transplantation, 2013
Grzegorczyk, Katarzyna, Weyde, Wacław, Klinger, Marian   +2 more
openaire   +1 more source

Current Position on the Role of Monomeric C-reactive Protein in Vascular Pathology and Atherothrombosis

Current Pharmaceutical Design, 2020
Sergey G Kozlov, Olga Saburova
exaly  

Dissociation of Pentameric to Monomeric C-Reactive Protein on Activated Platelets Localizes Inflammation to Atherosclerotic Plaques

Circulation Research, 2009
Su Eisenhardt, Andrew Murphy, Kevin J Woollard   +2 more
exaly  

Circulating microparticles generate and transport monomeric C-reactive protein in patients with myocardial infarction

Cardiovascular Research, 2012
Guy Krippner, Peter J Meikle, Su Eisenhardt   +2 more
exaly  

The mechanisms of kinesin motor motility: lessons from the monomeric motor KIF1A

Nature Reviews Molecular Cell Biology, 2009
Nobutaka Hirokawa, Ryo Nitta, Yasushi Okada   +2 more
exaly  

Plasma Levels of Endothelial Microparticles Bearing Monomeric C-reactive Protein are Increased in Peripheral Artery Disease

Journal of Cardiovascular Translational Research, 2016
JoAnn Trial, George E Taffet, Mark L Entman   +2 more
exaly