Results 31 to 40 of about 16,837 (135)

Identification of Key Active‐Site Positions Controlling the Chemoselectivity of Aspergillus Brasiliensis Unspecific Peroxygenase

open access: yesChemBioChem, Volume 26, Issue 10, May 27, 2025.
Unspecific peroxygenase (UPO) from Aspergillus brasiliensis AbrUPO catalyzes the aromatic hydroxylation of substituted benzenes. By integrating structural elements from well‐characterized UPOs in AbrUPO variants, position 186 was identified as a critical determinant of enzyme chemoselectivity.
Fabian Schmitz   +8 more
wiley   +1 more source

Converting Phenylacetone Monooxygenase into Phenylcyclohexanone Monooxygenase by Rational Design:Towards Practical Baeyer-Villiger Monooxygenases [PDF]

open access: yes, 2005
A homology model of the most frequently used, but thermally somewhat labile, Baeyer–Villiger monooxygenase, cyclohexanone monooxygenase (CHMO) has been derived on the basis of the recently published crystal structure of the thermally stable phenylacetone
Schulz, Frank   +11 more
core   +1 more source

Natural pigments derived from plants and microorganisms: classification, biosynthesis, and applications

open access: yesPlant Biotechnology Journal, Volume 23, Issue 2, Page 592-614, February 2025.
Summary Pigments, as coloured secondary metabolites, endow the world with a rich palette of colours. They primarily originate from plants and microorganisms and play crucial roles in their survival and adaptation processes. In this article, we categorize pigments based on their chemical structure into flavonoids, carotenoids, pyrroles, quinones ...
Qian Tang   +4 more
wiley   +1 more source

Effect of compound 1-13 on melanogenesis of melanoma cells and Parkinson’s disease-like injury [PDF]

open access: yes精准医学杂志
Objective To investigate the effect of compound 1-13 on melanogenesis of melanoma cells and Parkinson’s disease (PD)-like injury. Methods Enzyme activity assay was used to observe the effect of compound 1-13 on tyrosinase activity.
WANG Xiaohan, WANG Huanhuan, LI Qi
doaj  

Exploring Glutathione and Hypotaurine as Promising Antibrowning Agents: Safer Alternatives to Sulphites for Food and Beverage Preservation—A Concise Review

open access: yesJournal of Food Processing and Preservation, Volume 2025, Issue 1, 2025.
Oxidative browning poses a significant challenge in maintaining the visual appeal and nutritional quality of fresh‐cut food products and beverages. Traditional sulphites have been widely utilised for browning inhibition; however, concerns regarding their safety and allergenic potential have sparked the exploration of alternative options.
Kabezi Martine   +4 more
wiley   +1 more source

Catalytic cycles of the hydroxylation of monophenol and oxidation of o-diphenol to o-quinone by tyrosinase2.

open access: yes, 2014
Catalytic cycles of the hydroxylation of monophenol and oxidation of o-diphenol to o-quinone by tyrosinase2.
Qing-Xi Chen (538073)   +5 more
core   +1 more source

Genetic variation in the FMO2 gene: evolution & functional consequences [PDF]

open access: yes, 2011
PhDFlavin-containing monooxygenase 2 (FMO2) is involved in the metabolism of xenobiotics, including therapeutic drugs. FMO2 exists in two forms: a functional and a non-functional form.
Al-Sulaimani, Maha Saleh
core   +2 more sources

Tyrosinase Inhibition and Antimelanogenic Effects of Resorcinol‐Containing Compounds

open access: yesChemMedChem, Volume 19, Issue 23, December 2, 2024.
Resorcinol‐based compounds stand out as key inhibitors of tyrosinases (TYR) owing to their phenolic group's interaction with the dicopper centre and their ability to resist TYR‐mediated oxidation. While some well‐known examples are employed in dermatocosmetics and skin‐whitening products, this review covers the broader diversity of scaffolds, including
Morane Beaumet   +3 more
wiley   +1 more source

Grape skins (Vitis vinifera L.) catalyze the in vitro enzymatic hydroxylation of p-coumaric acid to caffeic acid

open access: yes, 2009
The ability of grape skins to catalyze in vitro conversion of p-coumaric acid to the more potent antioxidant caffeic acid was studied. Addition of different concentrations of p-coumaric to red grape skins (Cabernet Sauvignon) resulted in formation of ...
Arnous, Anis   +3 more
core   +1 more source

Hydroxytyrosol isolation, comparison of synthetic routes and potential biological activities

open access: yesFood Science &Nutrition, Volume 12, Issue 10, Page 6899-6912, October 2024.
Hydroxytyrosol (HT) is a polyphenol extracted from olive plant and its byproduct. This review highlights methods and pathways for the synthesis of hydroxytyrosol, providing insights based on its bioactivity characteristics, health benefits, and potential future applications.
Enhui Wang, Yanfei Jiang, Chunyue Zhao
wiley   +1 more source

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