Results 51 to 60 of about 27,891 (280)

Skin rash and mild bruising: Is montelukast a safe drug?

Indian Journal of Respiratory Care, 2018
Montelukast is one of the commonly used drugs in asthma patients. It is prescribed along with inhalational corticosteroids. Although a relatively safe drug, there is a probability of occurrence of skin rashes and skin bruising.
Deep Inder, Seema Manak, Faiz Akram, Pawan Kumar   +3 more
doaj   +1 more source

Leukotriene antagonists as first-line or add-on asthma controller therapy [PDF]

, 2011
Most randomized trials of treatment for asthma study highly selected patients under idealized conditions. METHODS: We conducted two parallel, multicenter, pragmatic trials to evaluate the real-world effectiveness of a leukotriene-receptor antagonist ...
Annie Blyth, Daryl Freeman, David Price, Ducharme FM, Edward C.F. Wilson, Elizabeth F. Juniper, Elizabeth V. Hillyer, Erika J. Sims, H. Miranda Mugford, Ian Harvey, Jamie Murdoch, Jon G. Ayres, Juniper EF, Lee Shepstone, Linda Kemp, Malmstrom K, O'Byrne PM, Richard F.T. Gilbert, Santanello NC, Stanley D. Musgrave, Stephanie Wolfe, Temple R, Thomas M   +22 more
core   +1 more source

Montelukast: The New Therapeutic Option for the Treatment of Epilepsy

Journal of Experimental Pharmacology, 2021
Currently, there is no definitive cure for epilepsy. The available medications relieve symptoms and reduce seizure attacks. The major challenge with the available antiepileptic medication is safety and affordability.
B. Tesfaye, Haftom Gebregergs Hailu, Kaleab Alemayehu Zewdie, Muluken Altaye Ayza, D. F. Berhe   +4 more
semanticscholar   +1 more source

Direct Activation of Sulfides by C–H Oxidation with Photoexcited Nitroarenes: Formal Manipulations of the C─S Bond

Angewandte Chemie, EarlyView.
Photochemical anaerobic oxidation of sulfides, using nitroarenes as bifunctional reagents, enables the formal manipulation of the C─S bond. The method allows direct and selective access to versatile carbonyl compounds from largely inert sulfides by C–H oxidation, thus avoiding multistep activation by sulfur oxidation.
Valentina D. Cuomo, Ciro Romano, David J. Procter   +2 more
wiley   +2 more sources

Montelukast alleviates inflammation in experimental autoimmune encephalomyelitis by altering Th17 differentiation in a mouse model

Immunology, 2021
Montelukast is a leukotriene receptor antagonist that is known to prevent allergic rhinitis and asthma. Blocking the Cysteinyl leukotriene receptor (CysLTR1), one of the primary receptors of leukotrienes, has been demonstrated to be efficacious in ...
B. Han, Yan-Yan Zhang, Ze Ye, Yun Xiao, J. Rasouli, Wen-Cheng Wu, Sumin Ye, Xin-Yue Guo, Lin Zhu, A. Rostami, Li-Bin Wang, Yuan Zhang, Xing Li   +12 more
semanticscholar   +1 more source

Is a Malleable Active Site Loop the Key to High Substrate Promiscuity? Hybrid, Biocatalytic Route to Structurally Diverse Taxoid Side Chains with Remarkable Dual Stereocontrol

Angewandte Chemie, EarlyView.
A highly stereoselective, dynamic reductive kinetic resolution (DYRKR) entry into myriad Taxotere‐like side chains with Clostridium acetobutylicum alcohol dehydrogenase (CaADH) enzyme is reported. Follow‐on cross couplings expand the structural diversity of the library (36 total examples).
Gaurav P. Kudalkar, Florian Leidner, Nivesh Kumar, Jared L. Hass, Peter Madzelan, Douglas R. Powell, Victor W. Day, Pierre Le Magueres, Joseph D. Ferrara, Lee M. Daniels, Akihito Yamano, Sho Ito, Wei Niu, Helmut Grubmüller, Mark A. Wilson, David B. Berkowitz   +15 more
wiley   +2 more sources

Montelukast in hospitalized patients diagnosed with COVID-19

Journal of Asthma, 2020
Objective Several therapeutic agents have been assessed for the treatment of COVID-19, but few approaches have been proven efficacious. Because leukotriene receptor antagonists, such as montelukast have been shown to reduce both cytokine release and lung
Ahsan Khan, Christian Misdary, N. Yegya-Raman, Sinae Kim, Navaneeth Narayanan, S. Siddiqui, P. Salgame, J. Radbel, F. D. Groote, C. Michel, J. Mehnert, Caleb Hernandez, T. Braciale, J. Malhotra, M. Gentile, S. Jabbour   +15 more
semanticscholar   +1 more source

Nonesophageal Eosinophilic Gastrointestinal Disorders: Clinical Care and Future Directions [PDF]

, 2018
Eosinophilic gastrointestinal disorders are a set of conditions with a wide range of clinical manifestations and treatment modalities. The disorders are suspected to result from an abnormal inflammatory response to allergen(s), and individuals may ...
Gupta, Sandeep K., Naramore, Sara
core   +1 more source

Successful use of montelukast in eosinophilic gastroenteritis: a case report and a literature review

BMC Gastroenterology, 2021
Background Eosinophilic gastrointestinal disorders, also known as eosinophilic gastroenteritis, are rare inflammatory conditions characterized by eosinophilic infiltration of different parts of the gastrointestinal tract, along with peripheral ...
Emran El-Alali, I. Abukhiran, Tarik Z. Alhmoud   +2 more
semanticscholar   +1 more source

Concentrations of Cysteinyl Leukotrienes in Various Biological Fluids of Children with Bronchial Asthma, Atopic Dermatitis and Food Protein Induced Enterocolitis [PDF]

, 2019
Clinical manifestation of food allergy is characterized by polymorphic cutaneous, respiratory and gastrointestinal syndromes. Leukotrienes occupy a key place in the pathogenesis of a wide range of inflammatory diseases, including bronchial asthma ...
Haiduchyk, H. (Halyna), Shadrin, O. (Oleg)   +1 more
core   +4 more sources