Results 41 to 50 of about 9,581 (161)
Clinical and Translational Allergy, Volume 16, Issue 8, August 2026.ABSTRACT Drug hypersensitivity reactions (DHRs) are a global health concern and remain challenging to investigate owing to the heterogeneity of endotypes and phenotypes, as well as the lack of standardized biomarkers. Until recently, strict drug avoidance was the only management strategy for severe DHRs.
Ana Maria Copaescu +13 more
wiley +1 more source
Population Genomics Insights into Pharmacogenomic Differentiation Between East Asians and Europeans
Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 510-519, August 2026.Genetic variation contributes substantially to interindividual and interpopulation differences in drug response, yet most pharmacogenomic studies remain biased toward European populations. Here, we systematically assessed pharmacogenomic variation across East Asians (EAS) and Europeans (EUR) using public genomic datasets and investigated the potential ...
Sihan Chen, Hongpu Chen, Shuhua Xu
wiley +1 more source
PROTECTIVE EFFECT OF MONTELUKAST AGAINST PENTYLENETETRAZOLE-INDUCED ACUTE SEIZURES AND KINDLING IN MICE [PDF]
Zagazig University Medical Journal, 2017 Background: Montelukast, a selective reversible cysteinyl leukotriene1 (CysLT1) receptor antagonist, is used in treatment of asthma, exercise induced-bronchospasm, allergic rhinitis and urticaria.
Zaki Abdel-kader +3 more
doaj +1 more source
A case report on the long‐term use of teduglutide in a pediatric patient with short bowel syndrome
Nutrition in Clinical Practice, Volume 41, Issue 4, Page 1253-1259, August 2026.Abstract Short bowel syndrome (SBS) is the leading cause of intestinal failure, frequently necessitating long‐term parenteral nutrition (PN). Teduglutide (TED), a glucagon‐like peptide‐2 analog, has demonstrated efficacy in reducing PN dependence in both adults and children. However, long‐term data in pediatric populations remain limited.
Tsuyoshi Sakurai +8 more
wiley +1 more source
Pediatric Mild Asthma: Bridging Current Gaps to Improve Future Care
Pediatric Pulmonology, Volume 61, Issue 8, August 2026.ABSTRACT Background Pediatric mild asthma is considered a benign condition, yet it accounts for a substantial proportion of morbidity. Characterization and management of children or adolescents with mild asthma are less explored than in adults, particularly due to its heterogeneous nature and variable course.
Francesca Santamaria +2 more
wiley +1 more source
Brazilian Journal of Medical and Biological ResearchMontelukast sodium is an effective and well-tolerated anti-asthmatic drug. Long non-coding RNAs (lncRNAs) are involved in the treatment of asthma. Therefore, this study aimed to investigate the effect of montelukast sodium on children with cough-variant ...
Zhenxing Xu +3 more
doaj +1 more source
Allergy, Volume 81, Issue 8, Page 2582-2632, August 2026.ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
Torsten Zuberbier +221 more
wiley +1 more source
Incidence and Early‐Life Risk Factors for Food Allergy in a Spanish Birth Cohort
Acta Paediatrica, Volume 115, Issue 8, Page 1654-1662, August 2026.ABSTRACT Aim The prevalence of food allergy has increased in recent decades. We aimed to determine the cumulative incidence of food allergy in early childhood and to identify associated risk factors. Methods We conducted a prospective birth cohort study including 1006 newborns recruited over one year at a single hospital in Spain and followed until 4 ...
Jorge García‐Ezquiaga +6 more
wiley +1 more source
Perspectives in Clinical ResearchIntroduction: Several fixed-dose combinations (FDCs) have been available for the treatment of allergic rhinitis (AR), of which montelukast and levocetirizine is one of the highly prescribed FDC.
Ganesh Natthuji Dakhale +3 more
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 7, July 2026.ABSTRACT Drug‐induced liver injury (DILI) is a leading cause of acute liver failure in the United States and remains difficult to predict and diagnose. Trimethoprim‐sulfamethoxazole (TMP‐SMX) is widely prescribed and generally well tolerated, yet rare cases of severe idiosyncratic hepatotoxicity have been reported.
Kaylie Duit +3 more
wiley +1 more source