Results 21 to 30 of about 9,581 (161)

The effects of Montelukast on depression and anxiety behaviors in rats

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objective: Montelukast is a leukotriene receptor antagonist used for the treatment of chronic asthma and to relieve symptoms of seasonal allergies.
Ersoz Gonca
doaj  

Impact of China's National Volume‐Based Procurement Policy on Cost, Volume, and Market Structure: An Interrupted Time‐Series Analysis of Montelukast Sodium

open access: yesHealth Care Science, EarlyView.
Using ARIMA‐based interrupted time‐series analysis, this study reveals that China's NVBP policy significantly reduced daily costs and enhanced affordability, driving generic substitution and the elimination of low‐quality products. Additionally, non‐winning manufacturers adopted strategic pricing behaviors to segment the market.
Yufei Cheng   +6 more
wiley   +1 more source

HPV‐6 Positive Eruptive Verruca Vulgaris After Upadacitinib Initiation for Severe Atopic Dermatitis

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Oral JAK‐1 inhibitors for atopic dermatitis (AD) are associated with an increased risk of cutaneous viral infections, particularly herpes zoster. Emerging case reports further suggest a link to eruptive human papillomavirus (HPV) disease. A 23‐year‐old transgender man (female‐to‐male) with severe AD developed a rapidly disseminating eruption ...
Mohammed Shanshal   +2 more
wiley   +1 more source

Sodium Ions Affect GPR17 Conformational States and Functionality

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Sodium is an allosteric modulator of several class‐A GPCR regulating active versus inactive conformation state and may be a critical issue for the optimization of crystallization procedures. Herein, the role of Na+ in the regulation of GPR17 conformational states was studied through MD simulations of GPR17 wild‐type and mutated on two ...
Luca Palazzolo   +6 more
wiley   +1 more source

Evaluating the antifibrotic potential of montelukast in preventing arthrofibrosis following total knee arthroplasty

open access: yesJournal of Orthopaedic Reports
Background: Arthrofibrosis causes debilitating stiffness and loss of range of motion following total knee arthroplasty (TKA). The primary treatment for early symptomatic stiffness is manipulation under anesthesia (MUA) within three months of index ...
Audrey Zhao   +5 more
doaj   +1 more source

Randomized controlled trial of fish oil and montelukast and their combination on airway inflammation and hyperpnea-induced bronchoconstriction. [PDF]

open access: yesPLoS ONE, 2010
Both fish oil and montelukast have been shown to reduce the severity of exercise-induced bronchoconstriction (EIB). The purpose of this study was to compare the effects of fish oil and montelukast, alone and in combination, on airway inflammation and ...
Sandra Tecklenburg-Lund   +5 more
doaj   +1 more source

Montelukast use over the past 20 years: monitoring of its effects and safety issues [PDF]

open access: yesClinical and Experimental Pediatrics, 2020
Montelukast, a leukotriene receptor antagonist, was launched 20 years ago in Korea. It is recommended as an alternative treatment for asthma in children with mild persistent symptoms or as an add-on treatment to existing low-dose inhaled corticosteroids (
Yong Ju Lee, Chang-Keun Kim
doaj   +1 more source

Treatment Dose Increase Versus Co‐Medication in Allergic Rhinitis: Systematic Review With Dose–Response Network Meta‐Analysis

open access: yesAllergy, EarlyView.
ABSTRACT Background To achieve adequate symptom control, patients with allergic rhinitis (AR) often need to increase their medication dose or add other treatments (co‐medication). We aimed to perform a systematic review to compare the efficacy and safety of AR medications for increased dose versus co‐medication.
Bernardo Sousa‐Pinto   +44 more
wiley   +1 more source

Evaluation of the effect of montelukast on cadmium induced toxicity in human embryonic kidney cells (HEK-293) [PDF]

open access: yesمجله علمی دانشگاه علوم پزشکی کردستان, 2019
Background and Aim: Industrialization of communities has resulted in a rise in cadmium accumulation in the plants, and also organs of human and animals. Kidney is the main target organ for cadmium accumulation and toxicity.
Farnoosh Kaviani   +4 more
doaj   +1 more source

Role of Montelukast in modulation of response to sepsis in preterm infants: a randomized-controlled trial

open access: yesEgyptian Pediatric Association Gazette, 2023
Background Since inflammatory mediators play a crucial role in the pathophysiology of neonatal sepsis. Montelukast, as an anti-inflammatory drug, could be a beneficial therapy.
Nouran El-Shehaby   +4 more
doaj   +1 more source

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