Results 51 to 60 of about 9,581 (161)

Montelukast deprescribing in outpatient specialty clinics: A single center cross-sectional study

open access: yesExploratory Research in Clinical and Social Pharmacy
Objective: To identify and evaluate montelukast deprescribing in outpatient specialty clinics. Methods: This was a single-center, retrospective, cross-sectional study conducted at an academic health system in the southern US including 21 specialty ...
David C. Foote   +5 more
doaj   +1 more source

A Double-Blind Non-inferiority Clinical Study of Montelukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, Compared with Pranlukast in Patients with Seasonal Allergic Rhinitis

open access: yesAllergology International, 2008
Background: During the course of development of montelukast, a cysteinyl leukotriene receptor 1 antagonist, for treatment of seasonal allergic rhinitis, a double-blind, non-inferiority study was carried out to evaluate the efficacy and safety of ...
Kimihiro Okubo, Kohtaro Baba
doaj   +1 more source

Anti-enzymatic and DNA docking studies of montelukast: A multifaceted molecular scaffold with in vitro investigations, molecular expression analysis and molecular dynamics simulations

open access: yesHeliyon
Montelukast, an approved leukotriene receptor 1 (Cys-LT 1) antagonist with anti-inflammatory properties is used for the treatment of asthma and allergic rhinitis. In the present studies, montelukast was subjected to in vitro inhibitory assays followed by
Shawana Abdullah   +8 more
doaj   +1 more source

Effects of montelukast on M2-related cytokine and chemokine in M2 macrophages

open access: yesJournal of Microbiology, Immunology and Infection, 2018
Background/Purpose: Asthma is a chronic airway inflammatory disease mediated by T-helper (Th)2 cells. Montelukast (trade name Singulair) is a cysteinyl leukotriene receptor antagonist used for asthma treatment.
Yi-Ching Lin   +6 more
doaj   +1 more source

APPLICATION EFFICIENCY OF MONTELUKAST AMONG CHILDREN SUFFERING FROM BRONCHIAL ASTHMA

open access: yesПедиатрическая фармакология, 2008
The article provides the results of montelukast efficiency depending on bronchial asthma severity level and the duration of a disease; the assessment of functional figures dynamics, disease pattern before and after the treatment with montelukast and the ...
A.K. Gevorkyan, E.A. Galeeva
doaj   +2 more sources

Relationship Between Gender and the Effectiveness of Montelukast: An Italian/Danish Register-Based Retrospective Cohort Study

open access: yesFrontiers in Pharmacology, 2018
Rationale: Gender-related differences in asthma prevalence, pathophysiology and clinical features induced by sex steroids have been investigated, however, how gender influences response to asthma treatments in routine clinical practice have not yet been ...
Maurizio Sessa   +16 more
doaj   +1 more source

Bronchoalveolar cytokine profiling identifies distinct endotypes in severe recurrent wheeze of infancy

open access: yes
Pediatric Allergy and Immunology, Volume 37, Issue 8, August 2026.
Alice Michel   +12 more
wiley   +1 more source

The Impact of Montelukast Duration on the Risk of Neuropsychiatric Disorders in Children with Asthma: A Population-Based Cohort Study

open access: yesPharmaceuticals
Background/Objectives: Asthma is one of the most common chronic diseases in children, and montelukast is widely prescribed to manage symptoms. However, concerns have emerged regarding its potential association with neuropsychiatric disorders.
Wei-Te Lei   +8 more
doaj   +1 more source

Attenuation of acute systemic inflammatory response after valve surgery

open access: yesJournal of Contemporary Medical Sciences, 2017
Objective This study highlights the protective effects of montelukast on myocardial ischemic reperfusion injury induced by cardiopulmonary bypass during valve replacement surgery.
Najah R. Hadi   +8 more
doaj  

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