LTA4H rs2660845 association with montelukast response in early and late-onset asthma.
PLoS ONE, 2021 Leukotrienes play a central pathophysiological role in both paediatric and adult asthma. However, 35% to 78% of asthmatics do not respond to leukotriene inhibitors.
Cyrielle Maroteau +18 more
doaj +1 more source
Meta-analysis of the efficacy and safety of Cimetidine Combined with Montelukast in the treatment of Henoch-Schonlein Purpura (HSP) in children [PDF]
, 2023 Wenqi Gu +7 more
openalex +1 more source
Efecto del aceite esencial de Minthostachys verticillata sobre la respuesta inmune de pacientes alérgicos a ácaros del polvo [PDF]
, 2009 El aceite esencial de hojas de M. verticillata fue obtenido por destilación en corriente de vapor y analizado por cromatografía gaseosa. Células mononucleares de sangre periférica de pacientes alérgicos, fueron estimuladas con aceite esencial.
Andrada, Melisa +6 more
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Nasal lysine aspirin challenge in the diagnosis of aspirin - exacerbated respiratory disease [PDF]
, 2013 Background Aspirin-exacerbated respiratory disease is under-diagnosed and therefore effective and inexpensive therapy with aspirin desensitization is rarely performed.
Darby, Y +6 more
core +1 more source
MedComm, Volume 7, Issue 2, February 2026.Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Inhibitory effect of calotropis gigantea extract on ovalbumin-induced airway inflammation and arachidonic acid induced inflammation in a murine model of asthma [PDF]
, 2011 The root of Calotropis gigantea has been reported as a traditional folkloric medicine in treatment of asthma in the Indian literature. Root contain α-and β-amyrin are reported to possess anti-lipoxygenase activity.
Vipin Bulani, Kailash Biyani, Ravindra Kale, Unmesh Joshi, Kishor Charhate, Dinesh Kumar, Ramesh Pagore, Int J Cur Bio Med Sci.
core
Treating asthma: is there a place for leukotriene receptor antagonists? [PDF]
, 2005 SummaryAsthma is a chronic disorder, characterized by airway hyperresponsiveness (AHR), airway inflammation and airway remodelling. Evidence has been provided for a relationship between pathophysiology, airway inflammation and remodelling.
Björn Sarrazin +8 more
core +3 more sources
Histopathological evaluation of induced pulmonary fibrosis under the effect of montelukast
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2023 Pulmonary fibrosis (PF) is an interstitial lung disease leading to scarring of the lung. There are several types of lung fibrosis as familial pulmonary fibrosis, idiopathic pulmonary fibrosis, and others associated with non-specific interstitial
Mohammed Rabah Mahdi +2 more
doaj +1 more source
Cysteinyl-leukotrienes contribute to sputum eosinophil chemotactic activity in asthmatics [PDF]
, 2006 Background: Cysteinyl-leukotrienes are lipid derived mediators involved in asthma. They are able to stimulate eosinophil chemotaxis in vitro. Induced sputum from asthmatics has been shown to contain eosinophil chemotactic activity.
Bousquet +17 more
core +1 more source
Addressing unmet needs for chronic kidney disease treatment in type 1 diabetes: A review
Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 16-26, January 2026.Abstract Chronic kidney disease (CKD) is a serious complication occurring in nearly one of three people with type 1 diabetes (T1D). Major therapeutic advances have been made in the management of CKD for people with type 2 diabetes (T2D), thereby improving their kidney, cardiovascular, and survival outcomes.
Katherine R. Tuttle +3 more
wiley +1 more source