Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. [PDF]
, 2016 Group 2 innate lymphoid cells (ILC2s) and type 2 helper T cells (Th2 cells) are the primary source of interleukin 5 (IL-5) and IL-13 during type 2 (allergic) inflammation in the lung.
Austen, K Frank +5 more
core +1 more source
Montelukast Prevents Mice Against Acetaminophen-Induced Liver Injury
Frontiers in Pharmacology, 2019 Acetaminophen (APAP) is a widely used over-the-counter antipyretic and analgesic drug. Overdose of APAP is the leading cause of hospital admission for acute liver failure.
Shiyun Pu +9 more
doaj +1 more source
, 2008 Case scenario A 4 year old girl, has been brought to the clinic by her parents due to three episodes of coughing and wheezing, with the first episode occurring approximately 6 months previously.
Formosa, Marie Claire
core +1 more source
Randomized controlled trial of fish oil and montelukast and their combination on airway inflammation and hyperpnea-induced bronchoconstriction. [PDF]
PLoS ONE, 2010 Both fish oil and montelukast have been shown to reduce the severity of exercise-induced bronchoconstriction (EIB). The purpose of this study was to compare the effects of fish oil and montelukast, alone and in combination, on airway inflammation and ...
Sandra Tecklenburg-Lund +5 more
doaj +1 more source
Montelukast sodium in cystic fibrosis [PDF]
Thorax, 2001 Many older patients with cystic fibrosis (CF) describe a component of their condition as “asthma” despite a lack of objective bronchial lability. We undertook a therapeutic trial of the leukotriene antagonist montelukast sodium in one such patient and observed a marked improvement in symptoms and peak expiratory flow rate (PEFR).
Alyn H. Morice, I. Aziz, Jack A Kastelik
openaire +3 more sources
Montelukast and Churg-Strauss syndrome [PDF]
Thorax, 2002 Several cases of eosinophilic conditions including Churg-Strauss syndrome (CSS) have recently been reported in asthmatic patients being treated with antileukotriene receptor antagonists. One patient with CSS who experienced a clinical relapse after treatment with montelukast and two asthmatic patients who developed CSS while receiving montelukast ...
R. Orriols +4 more
openaire +3 more sources
BMC ChemistryFor the treatment of rhinitis and asthma, a combination of Montelukast sodium and Bilastine has just been approved. Based on the first derivative of synchronous fluorescence, the current work developed a green, highly accurate, sensitive, and selective ...
S. Derayea +4 more
semanticscholar +1 more source
Montelukast, an Anti-asthmatic Drug, Inhibits Zika Virus Infection by Disrupting Viral Integrity
Frontiers in Microbiology, 2020 The association of Zika virus (ZIKV) infection and severe complications including neurological sequelae especially fetal microcephaly has aroused global attentions since its outbreak in 2015.
Yongkang Chen +3 more
semanticscholar +1 more source
Ratio of Leukotriene E-4 to Exhaled Nitric Oxide and the Therapeutic Response in Children With Exercise-Induced Bronchoconstriction [PDF]
, 2013 Purpose: This study assessed the association between the ratio of leukotriene E-4 (LTE4) to fractional exhaled nitric oxide (FENO) in the response of children with exercise-induced bronchoconstriction (EIB) enrolled in a therapeutic trial with ...
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core +1 more source
Impact of inhaled corticosteroids on growth in children with asthma: systematic review and meta-analysis [PDF]
, 2015 Background: Long-term inhaled corticosteroids (ICS) may reduce growth velocity and final height of children with asthma. We aimed to evaluate the association between ICS use of >12 months and growth.
A Bush +41 more
core +3 more sources