Results 61 to 70 of about 7,817,516 (255)

Sustained onabotulinumtoxinA therapeutic benefits in patients with chronic migraine over 3 years of treatment

The Journal of Headache and Pain, 2018
Background Evidence on whether the therapeutic effect and good safety profile of onabotulinumtoxinA (Botox®) in chronic migraine (CM) patients is maintained over long term treatment is still limited.
Michail Vikelis, Andreas A. Argyriou, Emmanouil V. Dermitzakis, Konstantinos C. Spingos, Nikolaos Makris, Evangelia Kararizou   +5 more
doaj   +1 more source

Interannual variability of ozone and carbon monoxide at the Whistler high elevation site: 2002–2006 [PDF]

Atmospheric Chemistry and Physics, 2011
In spring 2002, an atmospheric measurement site was established at the peak of Whistler Mountain in British Columbia, Canada to measure trace gases, particle chemistry and physics, and meteorology.
A. M. Macdonald, K. G. Anlauf, W. R. Leaitch, E. Chan, D. W. Tarasick   +4 more
doaj   +1 more source

MA22 - Mean monthly flows

, 2018
IHA metric describing mean monthly flow in m3 s-1.
Katie Irving (4517752)
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

MA14 - Mean monthly flows

, 2018
IHA metric describing mean monthly flow in m3 s-1.
Katie Irving (4517752)
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

MA12 - Mean monthly flows

, 2018
IHA metric describing mean monthly flow in m3 s-1.
Katie Irving (4517752)
core   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

Galcanezumab in episodic migraine: subgroup analyses of efficacy by high versus low frequency of migraine headaches in phase 3 studies (EVOLVE-1 & EVOLVE-2)

The Journal of Headache and Pain, 2019
Background Patients with high-frequency episodic migraine (HFEM) have a greater disease burden than those with low-frequency episodic migraine (LFEM).
Stephen D. Silberstein, Virginia L. Stauffer, Katie A. Day, Sarah Lipsius, Maria-Carmen Wilson   +4 more
doaj   +1 more source

Are the Nordic Stock Markets Mean Reverting? [PDF]

In this paper we test for mean reversion in the Nordic stock markets using monthly nominal data 1947-1998. By simply account for the heteroscedasticity of the data with a regime-switching model of normal distributions and taking estimation bias into ...
Graflund, Andreas
core