Results 61 to 70 of about 1,713,699 (394)
Reuse It Or Lose It: More Efficient Secure Computation Through Reuse of Encrypted Values [PDF]
, 2015 Two-party secure function evaluation (SFE) has become significantly more feasible, even on resource-constrained devices, because of advances in server-aided computation systems.
Butler, Kevin +3 more
core
A hidden cost of happiness in children.
, 2008 Happiness is generally considered an emotion with only beneficial effects, particularly in childhood. However, there are some situations where the style of information processing triggered by happiness could be a liability. In particular, happiness seems
Jaswal, Vikram K +2 more
core +1 more source
The immediate effects of 10-minute relaxation training on salivary immunoglobulin A (s-IgA) and mood state for Japanese female medical co-workers [PDF]
, 2007 This study examined the effects of relaxation training on salivary IgA (s-IgA) and mood state in Japanese female medical workers. Participants were enrolled and assigned to relaxation or control groups.
Hirokawa, Kumi +3 more
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
The Role of BDNF in the Neuroimmune Axis Regulation of Mood Disorders
Frontiers in Neurology, 2019 The neuroimmune system plays a crucial role in the regulation of mood disorders. Moreover, recent studies show that brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, is a key regulator in the neuroimmune axis.
Yang Jin +4 more
semanticscholar +1 more source
Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. [PDF]
, 2019 Mood disorders are highly prevalent and are the leading cause of disability worldwide. The neurobiological mechanisms underlying depression remain poorly understood, although theories regarding dysfunction within various neurotransmitter systems have ...
Dulawa, Stephanie C, Janowsky, David S
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Establishment and validation a relapse prediction model for bipolar disorder
Frontiers in PsychiatryBackgroundThe recurrence rate of bipolar disorder (BD) is relatively high. Assessing the risk of relapse in patients with BD can assist in identifying populations at high risk for recurrence, and early feasible interventions can improve patient ...
Xiaoqian Zhang +11 more
doaj +1 more source
Journal of Medical Internet Research, 2019 Background Virtually, all organisms on Earth have their own circadian rhythm, and humans are no exception. Circadian rhythms are associated with various human states, especially mood disorders, and disturbance of the circadian rhythm is known to be very ...
C. Cho +5 more
semanticscholar +1 more source
Hypohydration and Mood State in Free-Living Males and Females [PDF]
, 2015 Previous research has shown that acute dehydration can result in changes in mood. These changes have been reported in less than a 1% loss in total body water. However, the effect of hypohydration (i.e., reflected through high urine concentration) on mood
Vidal, Thomas Edward
core +2 more sources