Results 51 to 60 of about 672,834 (294)

Association between cognitive function and performance on effort based decision making in patients with major depressive disorder treated with Vortioxetine

Comprehensive Psychiatry, 2019
Background: It is well established that deficits in motivation, reward, and cognition are common during and in between syndromal episodes of depression as part of Major Depressive Disorder (MDD).
Mehala Subramaniapillai, Rodrigo B. Mansur, Hannah Zuckerman, Caroline Park, Yena Lee, Michelle Iacobucci, Bing Cao, Roger Ho, Kangguang Lin, Lee Phan, Roger S. McIntyre   +10 more
doaj   +1 more source

Probing the clinical and brain structural boundaries of bipolar and major depressive disorder

Translational Psychiatry, 2021
Bipolar disorder (BD) and major depressive disorder (MDD) have both common and distinct clinical features, that pose both conceptual challenges in terms of their diagnostic boundaries and practical difficulties in optimizing treatment.
Tao Yang, Sophia Frangou, Raymond W. Lam, Jia Huang, Yousong Su, Guoqing Zhao, Ruizhi Mao, Na Zhu, Rubai Zhou, Xiao Lin, Weiping Xia, Xing Wang, Yun Wang, Daihui Peng, Zuowei Wang, Lakshmi N. Yatham, Jun Chen, Yiru Fang   +17 more
doaj   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Mood profiling in Singapore: cross-cultural validation and potential applications of mood profile clusters [PDF]

, 2020
Mood profiling is a popular method of quantifying and classifying feeling states. Previous research has identified several novel mood profiles in predominantly Western English-speaking populations (Parsons-Smith et al., 2017), and replicated the findings
Parsons-Smith, Renee L., Terry, Peter C., Han, Christie S. Y.   +2 more
core   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

A qualitative study exploring depressed participants’ experiences of receiving Augmented Depression Therapy (ADepT)

BMJ Open
Objectives The current study aimed to explore participants’ views on the acceptability, impact and mechanisms of change of Augmented Depression Therapy (ADepT), a novel wellbeing-focused and recovery-oriented psychological therapy for depression.Design A
Rebecca Watson, Kim A Wright, Nigel Reed, Barney Dunn, Emily Widnall, Kalliopi Demetriou, Laura Warbrick, Katie Marchant, Nicole Geschwind, Isabella Magner-Parsons, Rachel Barter   +10 more
doaj   +1 more source

Mood dysregulation [PDF]

European Child & Adolescent Psychiatry, 2012
The publication of the DSM-5 is nearing, yet a debate continues about the boundaries of bipolar disorder (BP) in children and adolescents. This article focuses on two key components of this debate that are often treated under the collective term mood dysregulation: the first is chronic irritability (and the proposed DSM-5 category of disruptive mood ...
Mikita, Nina, Stringaris, Argyris
openaire   +4 more sources

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Does 24/7 care result in better outcomes for adults with eating disorders? A comparison of inpatient/residential care to partial hospitalization/intensive outpatient care for patients at low BMIs

Journal of Eating Disorders
Background Higher level of care (HLOC) treatment for eating disorders (EDs) is sometimes necessary, but research is lacking on whether HLOCs are actually more effective than less structured, lower levels of care.
Renee D. Rienecke, Dan V. Blalock, Alan Duffy, Craig Johnson, Megan Riddle, Daniel Le Grange, Philip S. Mehler, Harry A. Brandt   +7 more
doaj   +1 more source

More than Money: Social Class, Income, and the Intergenerational Persistence of Advantage

Sociological Science, 2017
I provide a uniquely comprehensive empirical integration of the sociological and economic approaches to the intergenerational transmission of advantage.
Carina Mood
doaj   +1 more source